IF (Immunofluorescence)
(Immunofluorescence analysis of HepG2 cells, using MLTK antibody.)
Rabbit anti-Human, Mouse MLTK Polyclonal Antibody | anti-MLTK antibody
MLTK Antibody
Gene Names
ZAK; pk; AZK; MLT; MRK; MLK7; MLTK; mlklak
Reactivity
Human, Mouse
Applications
Immunofluorescence, Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
MLTK, Antibody; MLTK Antibody; AZK; EC 2.7.11.25; MLTK; MRK-beta; mixed lineage kinase-related kinase; anti-MLTK antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total MLTK protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
800
Applicable Applications for anti-MLTK antibody
IF (Immunofluorescence), WB (Western Blot)
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from C-terminal of human MLTK.
Target Name
MLTK
Preparation and Storage
Store at -20 degree C
IF (Immunofluorescence)
(Immunofluorescence analysis of HepG2 cells, using MLTK antibody.)
IF (Immunofluorescence)
(Immunofluorescence analysis of HepG2 cells, using MLTK antibody.)
WB (Western Blot)
(Western blot analysis of extracts from HeLa cells, using MLTK antibody.)
WB (Western Blot)
(Western blot analysis of extracts from HeLa cells, using MLTK antibody.)
Related Product Information for anti-MLTK antibody
Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways. Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2. Isoform 1, but not isoform 2, causes cell shrinkage and disruption of actin stress fibers. Isoform 1 may have role in neoplastic cell transformation and cancer development. Isoform 1, but not isoform 2, phosphorylates histone H3 at 'Ser-28'.Gotoh I., J. Biol. Chem. 276:4276-4286(2001). Bloem L.J., J. Mol. Cell. Cardiol. 33:1739-1750(2001).Gross E.A., J. Biol. Chem. 277:13873-13882(2002).
Product Categories/Family for anti-MLTK antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
35,468 Da
NCBI Official Full Name
mitogen-activated protein kinase kinase kinase MLT isoform 1
NCBI Official Symbol
ZAK
NCBI Official Synonym Symbols
pk; AZK; MLT; MRK; MLK7; MLTK; mlklak
NCBI Protein Information
mitogen-activated protein kinase kinase kinase MLT
UniProt Protein Name
Mitogen-activated protein kinase kinase kinase MLT
UniProt Gene Name
ZAK
UniProt Synonym Gene Names
MLTK; HCCS-4; MLK-related kinase; MRK
UniProt Entry Name
MLTK_HUMAN
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Product Notes
The MLTK zak (Catalog #AAA302997) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The MLTK Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MLTK can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot). Researchers should empirically determine the suitability of the MLTK zak for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MLTK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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