IHC (Immunohistochemisry)
(Immunochemical staining of Mouse MMP-8 in Mouse skeletal muscle with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Mouse MMP-8 Polyclonal Antibody | anti-MMP8 antibody
Anti-MMP-8 Antibody, Rabbit Polyclonal
Gene Names
Mmp8; BB138268
Reactivity
Mouse
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Protein A & Antigen Affinity
Synonyms
MMP-8, Antibody; Anti-MMP-8 Antibody, Rabbit Polyclonal; MMP-8 Antibody, Rabbit PAb, Antigen Affinity Purified; matrix metallopeptidase 8; Anti-Mmp8 Antibody; anti-MMP8 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Mouse MMP-8
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-MMP8 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Immunogen
Recombinant Mouse MMP-8 Protein ( NP_032637.3; Met1-Ser465). MMP-8 specific IgG was purified by Mouse MMP-8 affinity chromatography.
Preparation and Storage
This antibody can be stored at 2 degree C-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
IHC (Immunohistochemisry)
(Immunochemical staining of Mouse MMP-8 in Mouse skeletal muscle with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohistochemisry)
(Immunochemical staining of Mouse MMP-8 in Mouse skeletal muscle with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohiostchemistry)
(Immunochemical staining of Mouse MMP-8 in Mouse spleen with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohiostchemistry)
(Immunochemical staining of Mouse MMP-8 in Mouse spleen with rabbit polyclonal antibody at 1:500 dilution, formalin-fixed paraffin embedded sections.)
WB (Western Blot)
(Anti-MMP8 rabbit polyclonal antibody at 1:500 dilutionLane A: NIH-3T3 Whole Cell LysateLysates/proteins at 30ug per lane.SecondaryGoat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution.Developed using the ECL technique. Performed under reducing conditions.Predicted band size:53 kDa)
WB (Western Blot)
(Anti-MMP8 rabbit polyclonal antibody at 1:500 dilutionLane A: NIH-3T3 Whole Cell LysateLysates/proteins at 30ug per lane.SecondaryGoat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution.Developed using the ECL technique. Performed under reducing conditions.Predicted band size:53 kDa)
Related Product Information for anti-MMP8 antibody
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Neutrophil collagenase, also known as Matrix metalloproteinase-8, MMP-8, and CLG1, is a member of the peptidase M1A family. MMP-8 may affect the metastatic behavior of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-8 in the tumor may have a protective effect against lymph node metastasis. MMP-8 may affect the metastatic behavior of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-8 participates in wound repair by contributing to the resolution of inflammation and open the possibility to develop new strategies for treating wound healing defects.
References
Hast. K.A.. e. al.,(1990). Huma. neutrophi. collagenase. . distinc. gen. produc. wit. homolog. t. othe. matri. metalloproteinases. J. Biol. Chem. 265:11421-11424.Blaese. J.. e. al.. (1991). Mercuria. activatio. o. huma. polymorphonuclea. leucocyt. procollagenase.Eur. J. Biochem. 202:1223-1230.Blaese. J.. e. al.,(1991). Mercuria. activatio. o. huma. polymorphonuclea. leucocyt. procollagenase. Eur. J. Biochem. 202:1223-1230.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
53,126 Da
NCBI Official Full Name
neutrophil collagenase preproprotein
NCBI Official Synonym Full Names
matrix metallopeptidase 8
NCBI Official Symbol
Mmp8
NCBI Official Synonym Symbols
BB138268
NCBI Protein Information
neutrophil collagenase
UniProt Protein Name
Neutrophil collagenase
UniProt Gene Name
Mmp8
UniProt Synonym Gene Names
MMP-8
UniProt Entry Name
MMP8_MOUSE
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Product Notes
The MMP8 mmp8 (Catalog #AAA259466) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-MMP-8 Antibody, Rabbit Polyclonal reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MMP-8 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the MMP8 mmp8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MMP-8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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