IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
Rabbit anti-Human MMP10 Polyclonal Antibody | anti-MMP10 antibody
MMP10 Antibody (C-term)
Gene Names
MMP10; SL-2; STMY2
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
MMP10, Antibody; MMP10 Antibody (C-term); Stromelysin-2; SL-2; Matrix metalloproteinase-10; MMP-10; Transin-2; MMP10; STMY2; anti-MMP10 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This MMP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 394-423 amino acids from the C-terminal region of human MMP10.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 1.31 (varies by lot)
Sequence Positions
394-423
Sequence Length
476
Applicable Applications for anti-MMP10 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
WB (Western Blot)
(Western blot analysis of hMMP10-R409 in mouse spleen tissue lysates (35ug/lane). MMP10 (arrow) was detected using the purified Pab.)
WB (Western Blot)
(Western blot analysis of hMMP10-R409 in mouse spleen tissue lysates (35ug/lane). MMP10 (arrow) was detected using the purified Pab.)
Related Product Information for anti-MMP10 antibody
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP10 degrades proteoglycans and fibronectin. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Product Categories/Family for anti-MMP10 antibody
References
Nagase, H., et al., J. Biol. Chem. 274(31):21491-21494 (1999).
Pendas, A.M., et al., Genomics 37(2):266-268 (1996).
Jung, J.Y., et al., Ann. Genet. 33(1):21-23 (1990).
Sirum, K.L., et al., Biochemistry 28(22):8691-8698 (1989).
Muller, D., et al., Biochem. J. 253(1):187-192 (1988).
Pendas, A.M., et al., Genomics 37(2):266-268 (1996).
Jung, J.Y., et al., Ann. Genet. 33(1):21-23 (1990).
Sirum, K.L., et al., Biochemistry 28(22):8691-8698 (1989).
Muller, D., et al., Biochem. J. 253(1):187-192 (1988).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
54151
NCBI Official Full Name
stromelysin-2 preproprotein
NCBI Official Synonym Full Names
matrix metallopeptidase 10
NCBI Official Symbol
MMP10
NCBI Official Synonym Symbols
SL-2; STMY2
NCBI Protein Information
stromelysin-2
UniProt Protein Name
Stromelysin-2
UniProt Gene Name
MMP10
UniProt Synonym Gene Names
STMY2; SL-2; MMP-10
UniProt Entry Name
MMP10_HUMAN
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Product Notes
The MMP10 mmp10 (Catalog #AAA284050) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 394-423. The MMP10 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's MMP10 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the MMP10 mmp10 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MMP10, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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