WB (Western Blot)
(MSX2 Antibody (Center) AAA284373 western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the MSX2 antibody detected the MSX2 protein (arrow).)
Rabbit MSX2 Polyclonal Antibody | anti-MSX2 antibody
MSX2 Antibody (Center)
Gene Names
MSX2; FPP; MSH; PFM; CRS2; HOX8; PFM1
Reactivity
Human (Predicted Reactivity: Chicken, Xenopus, Bovine, Mouse, Rat, Zebrafish)
Applications
ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
MSX2, Antibody; MSX2 Antibody (Center); Homeobox protein MSX-2; Homeobox protein Hox-8; MSX2; HOX8; anti-MSX2 antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Chicken, Xenopus, Bovine, Mouse, Rat, Zebrafish)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This MSX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-148 amino acids from the Central region of human MSX2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Sequence Positions
120-148
Sequence Length
267
Applicable Applications for anti-MSX2 antibody
ELISA, WB (Western Blot)
Function
Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antagonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter.
Cellular Location
Nucleus.
Preparation and Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(MSX2 Antibody (Center) AAA284373 western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the MSX2 antibody detected the MSX2 protein (arrow).)
WB (Western Blot)
(MSX2 Antibody (Center) AAA284373 western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the MSX2 antibody detected the MSX2 protein (arrow).)
Related Product Information for anti-MSX2 antibody
This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.
Product Categories/Family for anti-MSX2 antibody
References
Nikopensius, T., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 88(9):748-756(2010)
Satoh, K., et al. J. Gastroenterol. 45(7):763-770(2010)
Doi, T., et al. J. Pediatr. Surg. 45(6):1187-1191(2010)
Jagomagi, T., et al. Eur. J. Oral Sci. 118(3):213-220(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
Satoh, K., et al. J. Gastroenterol. 45(7):763-770(2010)
Doi, T., et al. J. Pediatr. Surg. 45(6):1187-1191(2010)
Jagomagi, T., et al. Eur. J. Oral Sci. 118(3):213-220(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
28897
NCBI Official Full Name
homeobox protein MSX-2
NCBI Official Synonym Full Names
msh homeobox 2
NCBI Official Symbol
MSX2
NCBI Official Synonym Symbols
FPP; MSH; PFM; CRS2; HOX8; PFM1
NCBI Protein Information
homeobox protein MSX-2
UniProt Protein Name
Homeobox protein MSX-2
UniProt Gene Name
MSX2
UniProt Synonym Gene Names
HOX8
UniProt Entry Name
MSX2_HUMAN
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Product Notes
The MSX2 msx2 (Catalog #AAA284373) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 120-148. The MSX2 Antibody (Center) reacts with Human (Predicted Reactivity: Chicken, Xenopus, Bovine, Mouse, Rat, Zebrafish) and may cross-react with other species as described in the data sheet. AAA Biotech's MSX2 can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the MSX2 msx2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MSX2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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