IHC (Immunohiostchemistry)
(Anti-MyD88 antibody, AAA45041, IHC(P)IHC(P): Human Tonsil Tissue)
Rabbit MyD88 Polyclonal Antibody | anti-MYD88 antibody
Anti-MyD88 antibody
Gene Names
MYD88; MYD88D
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
MyD88, Antibody; Anti-MyD88 antibody; Myeloid differentiation primary response protein MyD88; myeloid differentiation primary response gene(88); MYD 88 antibody; Myd88 antibody; MYD88_HUMAN antibody; MYD88D antibody; Myeloid differentiation marker 88 antibody; Myeloid differentiation primary response gene 88 antibody; Myeloid differentiation primary response gene antibody; Myeloid differentiation primary response protein MyD88 antibody; OTTHUMP00000161718 antibody; OTTHUMP00000208595 antibody; OTTHUMP00000209058 antibody; OTTHUMP00000209059 antibody; OTTHUMP00000209060 antibody; anti-MYD88 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
296
Applicable Applications for anti-MYD88 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human MyD88 (174-188aa FVQEMIRQLEQTNYR), different from the related rat and mouse sequences by one amino acid.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohiostchemistry)
(Anti-MyD88 antibody, AAA45041, IHC(P)IHC(P): Human Tonsil Tissue)
IHC (Immunohiostchemistry)
(Anti-MyD88 antibody, AAA45041, IHC(P)IHC(P): Human Tonsil Tissue)
WB (Western Blot)
(Anti-MyD88 antibody, AAA45041, Western blottingLane 1: Rat Spleen Tissue LysateLane 2: Rat Thymus Tissue LysateLane 3: JURKAT Cell LysateLane 4: RAJI Cell Lysate)
WB (Western Blot)
(Anti-MyD88 antibody, AAA45041, Western blottingLane 1: Rat Spleen Tissue LysateLane 2: Rat Thymus Tissue LysateLane 3: JURKAT Cell LysateLane 4: RAJI Cell Lysate)
Related Product Information for anti-MYD88 antibody
Description: Rabbit IgG polyclonal antibody for Myeloid differentiation primary response protein MyD88(MYD88) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: MYD88(MYELOID DIFFERENTIATION PRIMARY RESPONSE GENE 88), is a protein that, in humans, is encoded by the MYD88 gene. MyD88 is a key downstream adapter for most Toll-like receptors(TLRs) and interleukin-1 receptors(IL1Rs). And it is mapped on 3p22.2. MYD88 encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. Qverexpression of MYD88 caused an increase in the level of transcription from the interleukin-8 promoter. The C-terminal domain of MYD88 has significant sequence similarity to the cytoplasmic domain of IL1RAP. Inhibiting the IL1R-MYD88 pathway in vivo could block the damage from acute inflammation that occurs in response to sterile cell death, and do so in a way that might not compromise tissue repair or host defense against pathogens.
Background: MYD88(MYELOID DIFFERENTIATION PRIMARY RESPONSE GENE 88), is a protein that, in humans, is encoded by the MYD88 gene. MyD88 is a key downstream adapter for most Toll-like receptors(TLRs) and interleukin-1 receptors(IL1Rs). And it is mapped on 3p22.2. MYD88 encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. Qverexpression of MYD88 caused an increase in the level of transcription from the interleukin-8 promoter. The C-terminal domain of MYD88 has significant sequence similarity to the cytoplasmic domain of IL1RAP. Inhibiting the IL1R-MYD88 pathway in vivo could block the damage from acute inflammation that occurs in response to sterile cell death, and do so in a way that might not compromise tissue repair or host defense against pathogens.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
34,097 Da
NCBI Official Full Name
Myeloid differentiation primary response protein MyD88
NCBI Official Synonym Full Names
myeloid differentiation primary response 88
NCBI Official Symbol
MYD88
NCBI Official Synonym Symbols
MYD88D
NCBI Protein Information
myeloid differentiation primary response protein MyD88; myeloid differentiation primary response gene (88)
UniProt Protein Name
Myeloid differentiation primary response protein MyD88
UniProt Gene Name
MYD88
UniProt Entry Name
MYD88_HUMAN
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Product Notes
The MYD88 myd88 (Catalog #AAA45041) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-MyD88 antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's MyD88 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the MYD88 myd88 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MyD88, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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