Rabbit anti-Human, Mouse NDFIP1 Polyclonal Antibody | anti-NDFIP1 antibody

NDFIP1 Antibody

Cat. Num. AAA39963

• Gene Names: NDFIP1; N4WBP5
• Reactivity: Human, Mouse
• Applications: Western Blot, ELISA
• Purity: NDFIP1 Antibody is affinity chromatography purified via peptide column.
• Synonyms: NDFIP1, Antibody; NDFIP1 Antibody; NDFIP1; N4WBP5; PSEC0192; PSEC0223; NEDD4 family-interacting protein 1; Breast cancer-associated protein SGA-1M; anti-NDFIP1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: At least two isoforms of NDFIP1 are known to exist. NDFIP1 antibody is predicted to not cross-react with NDFIP2.
• Purity/Purification: NDFIP1 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 221

• Applicable Applications for anti-NDFIP1 antibody: WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: NDFIP1 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human NDFIP1.
• Buffer: NDFIP1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: NDFIP1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of NDFIP1 in human lung tissue with NDFIP1 antibody at 20 μg/ml.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of NDFIP1 in human lung tissue with NDFIP1 antibody at 5 μg/ml.)

WB (Western Blot)

(Western blot analysis of NDFIP1 in PC-3 cell lysate with NDFIP1 antibody at (A) 0.5 and (B) 1 μg/mL.)

Related Product Information for anti-NDFIP1 antibody

NDFIP1 Antibody: The NEDD4 family-interacting protein 1 (NDFIP1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains and is an integral Golgi membrane protein. It is a potential target for ubiquitination by the Nedd4 family of proteins. NDFIP1 is strongly expressed in surviving neurons following acute cortical brain injury, and overexpression in cultured cortical neurons increased survival following growth factor starvation, suggesting that NDFIP1 may play a role in neuronal survival. NDFIP1 and the related protein NDFIP2 are thought to interact with and regulate multiple components of the EGF and PTEN/Akt signaling pathways. Recent studies suggest that NDFIP1 may also play a role in Th17 differentiation by limiting the production of proinflammatory cytokines.

NCBI and Uniprot Product Information

• NCBI GI #: 13386480
• NCBI GeneID: 80762
• NCBI Accession #: NP_085048
• NCBI GenBank Nucleotide #: NM_030571.3
• UniProt Accession #: Q9BT67; Q658T8; Q8N2E3; Q8N2F9; B2RDB8; D3DQF0
• Molecular Weight: 24 kDa
• NCBI Official Full Name: NEDD4 family-interacting protein 1
• NCBI Official Synonym Full Names: Nedd4 family interacting protein 1
• NCBI Official Symbol: NDFIP1
• NCBI Official Synonym Symbols: N4WBP5
• NCBI Protein Information: NEDD4 family-interacting protein 1; Nedd4 WW domain-binding protein 5; putative MAPK-activating protein PM13; breast cancer-associated protein SGA-1M; putative NFKB and MAPK-activating protein; putative NF-kappa-B-activating protein 164
• UniProt Protein Name: NEDD4 family-interacting protein 1
• UniProt Gene Name: NDFIP1
• UniProt Synonym Gene Names: N4WBP5
• UniProt Entry Name: NFIP1_HUMAN