Rabbit Neurotrypsin Polyclonal Antibody | anti-PRSS12 antibody

Neurotrypsin Antibody

Cat. Num. AAA39249

• Gene Names: PRSS12; MRT1; BSSP3; BSSP-3
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: Neurotrypsin Antibody is affinity chromatography purified via peptide column.
• Synonyms: Neurotrypsin, Antibody; Neurotrypsin Antibody; Neurotrypsin; MRT1; BSSP3; BSSP-3; Leydin; protease, serine, 12 (neurotrypsin, motopsin); anti-PRSS12 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Neurotrypsin Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid; Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 875

• Applicable Applications for anti-PRSS12 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: Neurotrypsin antibody was raised against a 23 amino acid synthetic peptide from near the amino terminus of human neurotrypsin.; The immunogen is located within amino acids 110-160 of Neurotrypsin
• Positive Control: - (NIH) Cell Lysate; - Human Brain Tissue Slide
• Preparation and Storage: Neurotrypsin antibody can be stored at 4° for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IHC (Immunohistochemisry)

(Immunohistochemistry of Neurotrypsin in human brain tissue with Neurotrypsin antibody at 2.5 μg/mL.)

WB (Western Blot)

(Neurotrypsin AntibodyWestern blot analysis of neurotrypsin in 3T3 cell lysate with neurotrypsin antibody at (A) 0.25 and (B) 0.5 μg/mL.)

IF (Immunofluorescence)

(Immunofluorescence of Neurotrypsin in Human Brain cells with Neurotrypsin antibody at 20 μg/mL.)

Related Product Information for anti-PRSS12 antibody

Neurotrypsin Antibody: Neurotrypsin is a central nervous system-expressed serine protease whose truncation or absence causes nonsyndromic mental retardation. It is most prominently expressed in structures that are involved in the processing and storage of learned behavior and memory, such as the cerebral cortex, the hippocampus, and amygdala. Evidence suggests that neurotrypsin has multiple functions, including axonal outgrowth, maintaining neuronal plasticity, and arranging the perineuronal environment, partly in coordination with other proteases including tissue plasminogen activator. At least two isoforms of neurotrypsin are known to exist.

NCBI and Uniprot Product Information

• NCBI GI #: 2661424
• NCBI GeneID: 8492
• UniProt Accession #: P56730; Q9UP16
• Molecular Weight: Predicted: 96 kDa; Observed: 96 kDa
• NCBI Official Full Name: neurotrypsin
• NCBI Official Synonym Full Names: protease, serine, 12 (neurotrypsin, motopsin)
• NCBI Official Symbol: PRSS12
• NCBI Official Synonym Symbols: MRT1; BSSP3; BSSP-3
• NCBI Protein Information: neurotrypsin; leydin; brain-specific serine protease 3
• UniProt Protein Name: Neurotrypsin
• UniProt Gene Name: PRSS12
• UniProt Entry Name: NETR_HUMAN