WB (Western Blot)
(Western blot of PC-3 cell lysate with NF2 polyclonal antibody at 1:1000 dilution.)
Rabbit NF2/Merlin Polyclonal Antibody | anti-NF2/Merlin antibody
NF2/Merlin Polyclonal Antibody
Gene Names
NF2; ACN; SCH; BANF
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Antigen Affinity Purification
Synonyms
NF2/Merlin, Antibody; NF2/Merlin Polyclonal Antibody; ACN; BANF; Merlin; Neurofibromin 2; neurofibromin 2 (merlin); NF2; SCH; Schwannomerlin; Schwannomin; anti-NF2/Merlin antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Form/Format
PBS with 0.02% sodium azide,50% glycerol,pH 7.4
Concentration
2.2mg/ml (varies by lot)
Applicable Applications for anti-NF2/Merlin antibody
WB (Western Blot)
Immunogen
Recombinant Human NF2 protein expressed by E coli.
Research Area
Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Signal Transduction
Preparation and Storage
Storage: -20 degree C/One year. Avoid freeze/thaw cycles.
WB (Western Blot)
(Western blot of PC-3 cell lysate with NF2 polyclonal antibody at 1:1000 dilution.)
WB (Western Blot)
(Western blot of PC-3 cell lysate with NF2 polyclonal antibody at 1:1000 dilution.)
WB (Western Blot)
(Western blotting with anti-NF2 polyclonal Antibody at dilution of 1:1000. Lane 1: Mouse brain lysates, lane 2: Rat brain lysate.)
WB (Western Blot)
(Western blotting with anti-NF2 polyclonal Antibody at dilution of 1:1000. Lane 1: Mouse brain lysates, lane 2: Rat brain lysate.)
Related Product Information for anti-NF2/Merlin antibody
Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway,a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex.
Product Categories/Family for anti-NF2/Merlin antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
69,690 Da
NCBI Official Full Name
merlin isoform 1
NCBI Official Synonym Full Names
neurofibromin 2 (merlin)
NCBI Official Symbol
NF2
NCBI Official Synonym Symbols
ACN; SCH; BANF
NCBI Protein Information
merlin; schwannomin; schwannomerlin; neurofibromin-2; moesin-ezrin-radixin like; moesin-ezrin-radixin-like protein; moesin-ezrin-radizin-like protein; neurofibromin 2 (bilateral acoustic neuroma)
UniProt Protein Name
Merlin
UniProt Gene Name
NF2
UniProt Synonym Gene Names
SCH
UniProt Entry Name
MERL_HUMAN
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Product Notes
The NF2/Merlin nf2 (Catalog #AAA178659) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NF2/Merlin Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NF2/Merlin can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the NF2/Merlin nf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NF2/Merlin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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