IHC (Immunohiostchemistry)
(Fig: 2 Formalin-fixed, paraffin-embedded normal human bone marrow stained for NALP1 (CARD7/NAP) using NALP1 antibody at 1: 2000. Hematoxylin-eosin counterstain. Staining is seen in differentiated granulocytes.)
Rabbit anti-Human NLRP1/NALP1 Polyclonal Antibody | anti-NLRP1 antibody
Polyclonal Antibody to NLRP1/NALP1 (NAC-alpha)
Gene Names
NLRP1; NAC; MSPC; CARD7; CIDED; NALP1; SLEV1; DEFCAP; PP1044; VAMAS1; CLR17.1; DEFCAP-L/S
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, Immunoprecipitation
Purity
Serum
Synonyms
NLRP1/NALP1, Antibody; Polyclonal Antibody to NLRP1/NALP1 (NAC-alpha); NLRP1; CARD7; DEFCAP; KIAA0926; NAC; NALP1; Caspase recruitment domain-containing protein 7; Death effector filament-forming ced-4-like apoptosis protein; Nucleotide-binding domain and caspase recruitment domain; Antibody to NLRP1/NALP1 (NAC-alpha); Anti-NLRP1/NALP1 (NAC-alpha) Antibody; NLRP1/NALP1 (NAC-alpha) Antibody; anti-NLRP1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Serum
Form/Format
50 ul sera
Sequence Length
1473
Applicable Applications for anti-NLRP1 antibody
WB (Western Blot), IHC (Immunohistochemistry), IP (Immunoprecipitation)
Immunogen Information
A synthetic peptide of human NALP1 (NAC/CARD7) (amino acids 1058-1077 CVPSPASQGDLHTKPLGTDD) was used as immunogen for this antibody
Antigen
NLRP1/NALP1 (NAC-alpha)
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.
IHC (Immunohiostchemistry)
(Fig: 2 Formalin-fixed, paraffin-embedded normal human bone marrow stained for NALP1 (CARD7/NAP) using NALP1 antibody at 1: 2000. Hematoxylin-eosin counterstain. Staining is seen in differentiated granulocytes.)
IHC (Immunohiostchemistry)
(Fig: 2 Formalin-fixed, paraffin-embedded normal human bone marrow stained for NALP1 (CARD7/NAP) using NALP1 antibody at 1: 2000. Hematoxylin-eosin counterstain. Staining is seen in differentiated granulocytes.)
WB (Western Blot)
(Fig: 1 Western blot analysis of NALP1 (NAC/CARD7) in Jurkat cells using the NALP1 antibody at 1: 2000.)
WB (Western Blot)
(Fig: 1 Western blot analysis of NALP1 (NAC/CARD7) in Jurkat cells using the NALP1 antibody at 1: 2000.)
Related Product Information for anti-NLRP1 antibody
This antibody recognizes NALP1; human NALP1 is a 1473 amino acid protein, NALP1 (also known as NACHT, LRR and PYD containing protein 1) is a member of NALP CLR subfamily, has an N-terminal pyrin domain (PYD), followed by an NBD, LRR, and a C-terminal CARD domain. NALP1 is a component of both the inflammasome and apoptosome, suggesting that NALP1 has important roles in both inflammation and apoptosis.However, multiple splice variants encoding distinct NALP1 isoforms with varying amino acid lengths have been described and thus the molecular weight detected may vary depending on the isoform(s) expressed.
Product Categories/Family for anti-NLRP1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
46,068 Da
NCBI Official Full Name
NACHT, LRR and PYD domains-containing protein 1
NCBI Official Synonym Full Names
NLR family pyrin domain containing 1
NCBI Official Symbol
NLRP1
NCBI Official Synonym Symbols
NAC; MSPC; CARD7; CIDED; NALP1; SLEV1; DEFCAP; PP1044; VAMAS1; CLR17.1; DEFCAP-L/S
NCBI Protein Information
NACHT, LRR and PYD domains-containing protein 1
UniProt Protein Name
NACHT, LRR and PYD domains-containing protein 1
UniProt Gene Name
NLRP1
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Product Notes
The NLRP1 nlrp1 (Catalog #AAA78347) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to NLRP1/NALP1 (NAC-alpha) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NLRP1/NALP1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), IP (Immunoprecipitation). Researchers should empirically determine the suitability of the NLRP1 nlrp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NLRP1/NALP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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