Rabbit anti-Human NOD2 Polyclonal Antibody | anti-NOD2 antibody

NOD2 Antibody

Cat. Num. AAA39769

• Gene Names: NOD2; CD; ACUG; BLAU; IBD1; NLRC2; NOD2B; CARD15; CLR16.3; PSORAS1
• Reactivity: Human
• Applications: Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
• Purity: NOD2 Antibody is immunoaffinity chromatography purified IgG.
• Synonyms: NOD2, Antibody; NOD2 Antibody; NOD2; CD; ACUG; BLAU; IBD1; NLRC2; NOD2B; CARD15; CLR16.3; PSORAS1; Nucleotide-binding oligomerization domain-containing protein 2; Caspase recruitment domain-containing protein 15; nucleotide-binding oligomerization domain containing 2; anti-NOD2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: NOD2 has no cross-reaction with NOD1.
• Purity/Purification: NOD2 Antibody is immunoaffinity chromatography purified IgG.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 1040

• Applicable Applications for anti-NOD2 antibody: IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: Rabbit NOD2 polyclonal antibody was raised against a synthetic peptide corresponding to 14 amino acids at the carboxy terminus of human NOD2.
• Buffer: NOD2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: NOD2 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of NOD2 in HeLa cells with NOD2 antibody at 20 μg/mL.)

ICC (Immunocytochemistry)

(Immunocytochemistry of NOD2 in HeLa cells with NOD2 antibody at 10 μg/mL.)

WB (Western Blot)

(Western blot analysis of NOD2 in HeLa cell lysate with NOD2 antibody at (A) 2 and (B) 4 μg/mL.)

Related Product Information for anti-NOD2 antibody

NOD2 Antibody: Apaf-1 and NOD1 are members of a new family, which are involved in the regulation of apoptosis and immune response. Each of them contains a caspase recruitment domain (CARD) and a nucleotide-binding oligomerization domain (NOD). A third member in this family was recently identified and designated NOD2. NOD2 interacts with RICK via a homophilic CARD-CARD interaction. NOD2 activates NF-κB, which is regulated by its carboxy-terminal leucine-rich repeat domain that acts as an intracellular receptor for components of bacteria. The variants of NOD2, either a frameshift or a missense, were associated with Crohn's disease that is a main type of chronic inflammatory bowel disease.

NCBI and Uniprot Product Information

• NCBI GI #: 20137973
• NCBI GeneID: 64127
• UniProt Accession #: Q9HC29; Q96RH5; Q96RH6; Q96RH8; E2JEQ6
• Molecular Weight: 114 kDa
• NCBI Official Full Name: Nucleotide-binding oligomerization domain-containing protein 2
• NCBI Official Synonym Full Names: nucleotide-binding oligomerization domain containing 2
• NCBI Official Symbol: NOD2
• NCBI Official Synonym Symbols: CD; ACUG; BLAU; IBD1; NLRC2; NOD2B; CARD15; CLR16.3; PSORAS1
• NCBI Protein Information: nucleotide-binding oligomerization domain-containing protein 2; NOD-like receptor C2; NLR family, CARD domain containing 2; inflammatory bowel disease protein 1; caspase recruitment domain protein 15; nucleotide-binding oligomerization domain 2; caspase recruitment domain family, member 15; caspase recruitment domain-containing protein 15; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 2
• UniProt Protein Name: Nucleotide-binding oligomerization domain-containing protein 2
• UniProt Gene Name: NOD2
• UniProt Synonym Gene Names: CARD15; IBD1
• UniProt Entry Name: NOD2_HUMAN