ICC (Immunocytochemistry)
(Immunocytochemistry of NOD2 in Jurkat cells with NOD2 antibody at 5 ug/mL.)
Rabbit anti-Human NOD2 Polyclonal Antibody | anti-NOD2 antibody
NOD2 Antibody
Gene Names
NOD2; CD; ACUG; BLAU; IBD1; NLRC2; NOD2B; CARD15; CLR16.3; PSORAS1
Reactivity
Human
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Immunoaffinity chromatography purified IgG
Synonyms
NOD2, Antibody; NOD2 Antibody; Caspase recruitment domain 15, CARD15; anti-NOD2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
NOD2 has no cross-reaction with NOD1.
Purity/Purification
Immunoaffinity chromatography purified IgG
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
1013
Applicable Applications for anti-NOD2 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a synthetic peptide corresponding to 16 amino acids at the amino terminus of human NOD2.
Target Name
NOD2
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ICC (Immunocytochemistry)
(Immunocytochemistry of NOD2 in Jurkat cells with NOD2 antibody at 5 ug/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of NOD2 in Jurkat cells with NOD2 antibody at 5 ug/mL.)
WB (Western Blot)
(Western blot analysis of NOD2 in Jurkat cell lysate with NOD2 antibody at (A) 1, (B) 2 and (C) 4 ug/mL.)
WB (Western Blot)
(Western blot analysis of NOD2 in Jurkat cell lysate with NOD2 antibody at (A) 1, (B) 2 and (C) 4 ug/mL.)
Related Product Information for anti-NOD2 antibody
Apaf-1 and NOD1 are members of a new family, which are involved in the regulation of apoptosis and immune response. Each of them contains a caspase recruitment domain (CARD) and a nucleotide-binding oligomerization domain (NOD). A third member in this family was recently identified and designated NOD2. NOD2 interacts with RICK via a homophilic CARD-CARD interaction. NOD2 activates NF-kB, which is regulated by its carboxy-terminal leucine-rich repeat domain that acts as an intracellular receptor for components of bacteria. The variants of NOD2, either a frameshift or a missense, were associated with Crohn's disease that is a main type of chronic inflammatory bowel disease.
Product Categories/Family for anti-NOD2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
22,403 Da
NCBI Official Full Name
nucleotide-binding oligomerization domain-containing protein 2 isoform 2
NCBI Official Synonym Full Names
nucleotide-binding oligomerization domain containing 2
NCBI Official Symbol
NOD2
NCBI Official Synonym Symbols
CD; ACUG; BLAU; IBD1; NLRC2; NOD2B; CARD15; CLR16.3; PSORAS1
NCBI Protein Information
nucleotide-binding oligomerization domain-containing protein 2
UniProt Protein Name
Nucleotide-binding oligomerization domain-containing protein 2
UniProt Gene Name
NOD2
UniProt Synonym Gene Names
CARD15; IBD1
UniProt Entry Name
NOD2_HUMAN
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Product Notes
The NOD2 nod2 (Catalog #AAA307014) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NOD2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NOD2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the NOD2 nod2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NOD2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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