Rabbit anti-Mouse NPHS1 Polyclonal Antibody | anti-NPHS1 antibody
NPHS1 Polyclonal Antibody
Gene Names
Nphs1; nephrin; NephrinB
Reactivity
Mouse
Applications
Immunohistochemistry
Purity
Affinity Purification
Synonyms
NPHS1, Antibody; NPHS1 Polyclonal Antibody; CNF; Nephrin; Nephrosis 1 congenital Finnish type; Nephrosis 1; congenital; Finnish type (nephrin); NPHN; NPHS 1; Nphs1; Renal glomerulus specific cell adhesion receptor; Renal glomerulus-specific cell adhesion receptor; anti-NPHS1 antibody
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Form/Format
PBS with 0.02% sodium azide, 100 ug/ml BSA and 50% glycerol.
Sequence Length
1,242
Applicable Applications for anti-NPHS1 antibody
IHC (Immunohistochemistry)
Immunogen
KLH conjugated synthetic peptide corresponding to Mouse Nephrin
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Related Product Information for anti-NPHS1 antibody
This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.In Western blots, nephrin antibodies generated against the two terminal extracellular Ig domains of recombinant human nephrin recognized a 180-kDa protein in lysates of human glomeruli and a 150-kDa protein in transfected COS-7 cell lysates.
Product Categories/Family for anti-NPHS1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
nephrin
NCBI Official Synonym Full Names
nephrosis 1, nephrin
NCBI Official Symbol
Nphs1
NCBI Official Synonym Symbols
nephrin; NephrinB
NCBI Protein Information
nephrin
UniProt Protein Name
Nephrin
UniProt Gene Name
Nphs1
UniProt Synonym Gene Names
Nphn
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Product Notes
The NPHS1 nphs1 (Catalog #AAA174481) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NPHS1 Polyclonal Antibody reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's NPHS1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the NPHS1 nphs1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NPHS1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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