WB (Western Blot)
(WB Suggested Anti-NR3C2 Antibody Titration: 1.25ug/mlPositive Control: A172 cell lysateNR3C2 is supported by BioGPS gene expression data to be expressed in A172)
Rabbit NR3C2 Polyclonal Antibody | anti-NR3C2 antibody
NR3C2 antibody - middle region
Gene Names
NR3C2; MR; MCR; MLR; NR3C2VIT
Reactivity
Cow, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Protein A purified
Synonyms
NR3C2, Antibody; NR3C2 antibody - middle region; anti-NR3C2 antibody
Host
Rabbit
Reactivity
Cow, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
Clonality
Polyclonal
Purity/Purification
Protein A purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Sequence
Synthetic peptide located within the following region: RRKNCPACRLQKCLQAGMNLGARKSKKLGKLKGIHEEQPQQQQPPPPPPP
Sequence Length
984
Applicable Applications for anti-NR3C2 antibody
WB (Western Blot), IHC (Immunohistochemistry)
Homology
Cow: 83%; Guinea Pig: 75%; Horse: 86%; Human: 100%; Mouse: 92%; Pig: 93%; Rabbit: 100%; Rat: 92%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human NR3C2
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(WB Suggested Anti-NR3C2 Antibody Titration: 1.25ug/mlPositive Control: A172 cell lysateNR3C2 is supported by BioGPS gene expression data to be expressed in A172)
WB (Western Blot)
(WB Suggested Anti-NR3C2 Antibody Titration: 1.25ug/mlPositive Control: A172 cell lysateNR3C2 is supported by BioGPS gene expression data to be expressed in A172)
IHC (Immunohistochemistry)
(Human kidney)
IHC (Immunohistochemistry)
(Human kidney)
Related Product Information for anti-NR3C2 antibody
This is a rabbit polyclonal antibody against NR3C2. It was validated on Western Blot and immunohistochemistry
Target Description: NR3C2 is a receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. It binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
Target Description: NR3C2 is a receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. It binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
Product Categories/Family for anti-NR3C2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
107kDa
NCBI Official Full Name
mineralocorticoid receptor isoform 1
NCBI Official Synonym Full Names
nuclear receptor subfamily 3 group C member 2
NCBI Official Symbol
NR3C2
NCBI Official Synonym Symbols
MR; MCR; MLR; NR3C2VIT
NCBI Protein Information
mineralocorticoid receptor
UniProt Protein Name
Mineralocorticoid receptor
UniProt Gene Name
NR3C2
UniProt Synonym Gene Names
MCR; MLR; MR
UniProt Entry Name
MCR_HUMAN
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Product Notes
The NR3C2 nr3c2 (Catalog #AAA199571) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NR3C2 antibody - middle region reacts with Cow, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NR3C2 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the NR3C2 nr3c2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: RRKNCPACRL QKCLQAGMNL GARKSKKLGK LKGIHEEQPQ QQQPPPPPPP. It is sometimes possible for the material contained within the vial of "NR3C2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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