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ICC (Immunocytochemistry)
(Anti-NRG1 antibody, AAA45419, ICCICC: HELA Cell)
Rabbit NRG1 Polyclonal Antibody | anti-NRG1 antibody
Anti-NRG1 antibody
Gene Names
NRG1; GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; MSTP131; NRG1-IT2
Reactivity
Human, Mouse, Rat
Applications
Immunocytochemistry, Immunohistochemistry, Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
NRG1, Antibody; Anti-NRG1 antibody; Pro-neuregulin-1, membrane-bound isoform; neuregulin 1; Acetylcholine receptor inducing activity antibody; Acetylcholine receptor-inducing activity antibody; ARIA antibody; Breast cancer cell differentiation factor p45 antibody; GGF antibody; GGF2 antibody; Glial growth factor antibody; heregulin antibody; heregulin, alpha(45kD, ERBB2 p185-activator) antibody; HGL antibody; HRG antibody; HRG1 antibody; HRGA antibody; MST131 antibody; NDF antibody; Neu differentiation factor antibody; Neuregulin 1 antibody; neuregulin 1 type IV beta 1a antibody; neuregulin 1 type IV beta 3 antibody; Neuregulin-1 antibody; NRG 1 antibody; nrg1 antibody; NRG1_HUMAN antibody; OTTHUMP00000225398 antibody; OTTHUMP00000225419 antibody; OTTHUMP00000225420 antibody; OTTHUMP00000225421 antibody; OTTHUMP00000225422 antibody; OTTHUMP00000225477 antibody; OTTHUMP00000225545 antibody; OTTHUMP00000230603 antibody; OTTHUMP00000230605 antibody; Pro-NRG1 antibody; ProNRG1 antibody; Sensory and motor neuron-derived factor antibody; SMDF antibody; anti-NRG1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
640
Applicable Applications for anti-NRG1 antibody
ICC (Immunocytochemistry), IHC (Immunohistochemistry), IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human NRG1 (617-636aa RFSTQEEIQARLSSVIANQD), different from the related rat and mouse sequences by one amino acids.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
ICC (Immunocytochemistry)
(Anti-NRG1 antibody, AAA45419, ICCICC: HELA Cell)
ICC (Immunocytochemistry)
(Anti-NRG1 antibody, AAA45419, ICCICC: HELA Cell)
IHC (Immunohistochemistry)
(Anti-NRG1 antibody, AAA45419, IHC(F)IHC(F): Rat Intestine Tissue)
IHC (Immunohistochemistry)
(Anti-NRG1 antibody, AAA45419, IHC(F)IHC(F): Rat Intestine Tissue)
WB (Western Blot)
(Anti-NRG1 antibody, AAA45419, Western blottingLane 1: Rat Spleen Tissue LysateLane 2: Rat Kidney Tissue LysateLane 3: Rat Brain Tissue LysateLane 4: HELA Cell LysateLane 5: SMMC Cell Lysate)
WB (Western Blot)
(Anti-NRG1 antibody, AAA45419, Western blottingLane 1: Rat Spleen Tissue LysateLane 2: Rat Kidney Tissue LysateLane 3: Rat Brain Tissue LysateLane 4: HELA Cell LysateLane 5: SMMC Cell Lysate)
IHC (Immunohiostchemistry)
(Anti-NRG1 antibody, AAA45419, IHC(P)IHC(P): Human Intestinal Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti-NRG1 antibody, AAA45419, IHC(P)IHC(P): Human Intestinal Cancer Tissue)
IHC (Immunohistochemistry)
(Anti-NRG1 antibody, AAA45419, IHC(P)IHC(P): Rat Intestine Tissue)
IHC (Immunohistochemistry)
(Anti-NRG1 antibody, AAA45419, IHC(P)IHC(P): Rat Intestine Tissue)
Related Product Information for anti-NRG1 antibody
Description: Rabbit IgG polyclonal antibody for Pro-neuregulin-1, membrane-bound isoform(NRG1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human, Mouse, Rat.
Background: NRG1(Neuregulin 1), also known as ARIA, NDF or HRGA, is a protein that in humans is encoded by the NRG1 gene. NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. By in situ hybridization of a tritium-labeled probe to human metaphase spreads, Orr-Urtreger et al.(1993) localized the NDF gene to 8p21-p12. In mouse embryos 14.5 days postcoitum, Orr-Urtreger et al.(1993) found that NDF expression is confined predominantly to the central and peripheral nervous systems, including the neuroepithelium that lines the lateral ventricles of the brain, the ventral horn of the spinal cord, and the intestinal as well as dorsal root ganglia.
Background: NRG1(Neuregulin 1), also known as ARIA, NDF or HRGA, is a protein that in humans is encoded by the NRG1 gene. NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. By in situ hybridization of a tritium-labeled probe to human metaphase spreads, Orr-Urtreger et al.(1993) localized the NDF gene to 8p21-p12. In mouse embryos 14.5 days postcoitum, Orr-Urtreger et al.(1993) found that NDF expression is confined predominantly to the central and peripheral nervous systems, including the neuroepithelium that lines the lateral ventricles of the brain, the ventral horn of the spinal cord, and the intestinal as well as dorsal root ganglia.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
46,226 Da
NCBI Official Full Name
Pro-neuregulin-1, membrane-bound isoform
NCBI Official Synonym Full Names
neuregulin 1
NCBI Official Symbol
NRG1
NCBI Official Synonym Symbols
GGF; HGL; HRG; NDF; ARIA; GGF2; HRG1; HRGA; SMDF; MST131; MSTP131; NRG1-IT2
NCBI Protein Information
pro-neuregulin-1, membrane-bound isoform; pro-NRG1; glial growth factor; neu differentiation factor; sensory and motor neuron derived factor; heregulin, alpha (45kD, ERBB2 p185-activator)
UniProt Protein Name
Pro-neuregulin-1, membrane-bound isoform
UniProt Gene Name
NRG1
UniProt Synonym Gene Names
GGF; HGL; HRGA; NDF; SMDF; Pro-NRG1; ARIA; HRG
UniProt Entry Name
NRG1_HUMAN
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Product Notes
The NRG1 nrg1 (Catalog #AAA45419) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-NRG1 antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NRG1 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), IHC (Immunohistochemistry), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the NRG1 nrg1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NRG1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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