IHC (Immunohiostchemistry)
(Mouse Ntrk2 Antibody (Center) (AAA285018)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Ntrk2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit Ntrk2 Polyclonal Antibody | anti-Ntrk2 antibody
Mouse Ntrk2 Antibody (Center)
Gene Names
Ntrk2; Tkrb; trkB; trk-B; GP145-TrkB/GP95-TrkB
Reactivity
Mouse (Predicted Reactivity: Rat)
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
Ntrk2, Antibody; Mouse Ntrk2 Antibody (Center); BDNF/NT-3 growth factors receptor; GP145-TrkB/GP95-TrkB; Trk-B; Neurotrophic tyrosine kinase receptor type 2; TrkB tyrosine kinase; Ntrk2; Trkb; anti-Ntrk2 antibody
Host
Rabbit
Reactivity
Mouse (Predicted Reactivity: Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This Mouse Ntrk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-372 amino acids from the Central region of mouse Ntrk2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.49 (varies by lot)
Sequence Positions
343-372
Sequence Length
749
Applicable Applications for anti-Ntrk2 antibody
WB (Western Blot), IHC (Immunohistochemistry), ELISA
Antigen Type
Synthetic Peptide
Antigen Source
MOUSE
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Mouse Ntrk2 Antibody (Center) (AAA285018)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Ntrk2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(Mouse Ntrk2 Antibody (Center) (AAA285018)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Ntrk2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(Western blot analysis of lysate from mouse NIH/3T3 cell line, using Mouse Ntrk2 Antibody (Center). AAA285018 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.)
WB (Western Blot)
(Western blot analysis of lysate from mouse NIH/3T3 cell line, using Mouse Ntrk2 Antibody (Center). AAA285018 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.)
Related Product Information for anti-Ntrk2 antibody
Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.
Product Categories/Family for anti-Ntrk2 antibody
References
Xu, X., et al. Proc. Natl. Acad. Sci. U.S.A. 107(44):19126-19131(2010)
Lobo, M.K., et al. Science 330(6002):385-390(2010)
Gascon, E., et al. J. Neurosci. 30(37):12414-12423(2010)
Nikoletopoulou, V., et al. Nature 467(7311):59-63(2010)
Ohnishi, H., et al. J. Neurosci. 30(31):10472-10483(2010)
Lobo, M.K., et al. Science 330(6002):385-390(2010)
Gascon, E., et al. J. Neurosci. 30(37):12414-12423(2010)
Nikoletopoulou, V., et al. Nature 467(7311):59-63(2010)
Ohnishi, H., et al. J. Neurosci. 30(31):10472-10483(2010)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
92133
NCBI Official Full Name
BDNF/NT-3 growth factors receptor isoform a
NCBI Official Synonym Full Names
neurotrophic tyrosine kinase, receptor, type 2
NCBI Official Symbol
Ntrk2
NCBI Official Synonym Symbols
Tkrb; trkB; trk-B; GP145-TrkB/GP95-TrkB
NCBI Protein Information
BDNF/NT-3 growth factors receptor
UniProt Protein Name
BDNF/NT-3 growth factors receptor
UniProt Gene Name
Ntrk2
UniProt Synonym Gene Names
Trkb; Trk-B
UniProt Entry Name
NTRK2_MOUSE
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Product Notes
The Ntrk2 ntrk2 (Catalog #AAA285018) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 343-372. The Mouse Ntrk2 Antibody (Center) reacts with Mouse (Predicted Reactivity: Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's Ntrk2 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the Ntrk2 ntrk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Ntrk2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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