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product-image-AAA40791_IF11.jpg IF (Immunofluorescence) (Immunofluorescence of OASL1 in HepG2 cells with OASL1 antibody at 20 μg/mL.)

Rabbit OASL Polyclonal Antibody | anti-OASL antibody

OASL Antibody

Gene Names
OASL; OASLd; TRIP14; TRIP-14; p59OASL; p59 OASL; p59-OASL
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
Purity
OASL antibody is affinity chromatography purified via peptide column.
Synonyms
OASL, Antibody; OASL Antibody; OASL; OASLd; TRIP14; TRIP-14; p59OASL; p59 OASL; p59-OASL; Thyroid receptor-interacting protein 14; TR-interacting protein 14; 2'-5'-oligoadenylate synthetase-like; anti-OASL antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
OASL antibody is human, mouse and rat reactive.
Purity/Purification
OASL antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
514
Applicable Applications for anti-OASL antibody
IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
OASL antibody was raised against a 17 amino acid peptide near the amino terminus of human OASL.
Buffer
OASL Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
OASL antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.

IF (Immunofluorescence)

(Immunofluorescence of OASL1 in HepG2 cells with OASL1 antibody at 20 μg/mL.)

product-image-AAA40791_IF11.jpg IF (Immunofluorescence) (Immunofluorescence of OASL1 in HepG2 cells with OASL1 antibody at 20 μg/mL.)

ICC (Immunocytochemistry)

(Immunocytochemistry of OASL1 in HepG2 cells with OASL1 antibody at 2.5 μg/mL.)

product-image-AAA40791_ICC13.jpg ICC (Immunocytochemistry) (Immunocytochemistry of OASL1 in HepG2 cells with OASL1 antibody at 2.5 μg/mL.)

WB (Western Blot)

(Western blot analysis of OASL in mouse bladder tissue lysate with OASL antibody at 1 μg/ml.)

product-image-AAA40791_WB15.gif WB (Western Blot) (Western blot analysis of OASL in mouse bladder tissue lysate with OASL antibody at 1 μg/ml.)
Related Product Information for anti-OASL antibody
OASL (2'-5'-oligoadenylate synthetase-like), also known as p59OASL or TRIP14 (thyroid receptor-interacting protein 14), is a 514 amino acid protein that exists as two alternatively spliced isoforms, designated p56 and p30, and contains two ubiquitin-like domains (1). It is widely expressed in a variety of tissues and interacts with the ligand binding domain of the thyroid receptor (TR) and is able to bind double-stranded RNA and DNA, possibly playing a role in RNA degradation and the overall inhibition of protein synthesis (2-3). Methyl CpG-binding protein 1 (MBD1), which functions as a transcriptional repressor, was identified as a strong p59 OASL interactor (4).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Predicted: 57 kDa

Observed: 65 kDa
NCBI Official Full Name
2'-5'-oligoadenylate synthase-like protein isoform a
NCBI Official Synonym Full Names
2'-5'-oligoadenylate synthetase-like
NCBI Official Symbol
OASL
NCBI Official Synonym Symbols
OASLd; TRIP14; TRIP-14; p59OASL; p59 OASL; p59-OASL
NCBI Protein Information
2'-5'-oligoadenylate synthase-like protein; 2'-5'-OAS-RP; 2'-5'-OAS-related protein; TR-interacting protein 14; thyroid receptor-interacting protein 14; 59 kDa 2'-5'-oligoadenylate synthase-like protein; 59 kDa 2'-5'-oligoadenylate synthetase-like protein
UniProt Protein Name
2'-5'-oligoadenylate synthase-like protein
UniProt Gene Name
OASL
UniProt Synonym Gene Names
TRIP14; 2'-5'-OAS-RP; TR-interacting protein 14; TRIP-14; p59OASL
UniProt Entry Name
OASL_HUMAN

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Product Notes

The OASL oasl (Catalog #AAA40791) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The OASL Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's OASL can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the OASL oasl for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OASL, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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