IP (Immunoprecipitation)
(Detection of human OSR1 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-OSR1 antibody AAA211540 used for IP at 3 ug/mg lysate. OSR1 was also immunoprecipitated by rabbit anti-OSR1 antibody which recognizes a downstream epitope. For blotting immunoprecipitated OSR1, was used at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 1 second.)
Rabbit anti-Human OSR1 Polyclonal Antibody | anti-OSR1 antibody
Rabbit anti-OSR1 Antibody, Affinity Purified
Gene Names
OXSR1; OSR1
Reactivity
Human
Applications
Immunohistochemistry, Immunoprecipitation
Purity
Antigen Affinity Purified
Synonyms
OSR1, Antibody; Rabbit anti-OSR1 Antibody, Affinity Purified; OSR1; oxidative stress-responsive 1 protein; serine/threonine-protein kinase OSR1; Serine/threonine-protein kinase OSR1; oxidative stress responsive 1; anti-OSR1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Concentration
1000ug/ml (varies by lot)
Applicable Applications for anti-OSR1 antibody
IHC (Immunohistochemistry), IP (Immunoprecipitation)
Immunogen
Between 300 and 350
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Shelf Life: 1 year from date of receipt
IP (Immunoprecipitation)
(Detection of human OSR1 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-OSR1 antibody AAA211540 used for IP at 3 ug/mg lysate. OSR1 was also immunoprecipitated by rabbit anti-OSR1 antibody which recognizes a downstream epitope. For blotting immunoprecipitated OSR1, was used at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 1 second.)
IP (Immunoprecipitation)
(Detection of human OSR1 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-OSR1 antibody AAA211540 used for IP at 3 ug/mg lysate. OSR1 was also immunoprecipitated by rabbit anti-OSR1 antibody which recognizes a downstream epitope. For blotting immunoprecipitated OSR1, was used at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 1 second.)
IHC (Immunohistochemistry)
(Detection of human OSR1 by immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-OSR1 (Cat. No. AAA211540 Lot1) used at a dilution of 1:1,000 (1ug/ml). Detection: DAB)
IHC (Immunohistochemistry)
(Detection of human OSR1 by immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-OSR1 (Cat. No. AAA211540 Lot1) used at a dilution of 1:1,000 (1ug/ml). Detection: DAB)
Related Product Information for anti-OSR1 antibody
Oxidative stress responsive 1 (OSR1) is a STE20-related kinase involved in ion transport and fluid and ion homeostasis. OSR1 interacts with SPAK (STE20/SPS1-reated proline/alanine-rich kinase) and together are activated by the upstream kinase WNK1 [with no K (lysine) protein kinase-1]. Activation of OSR1 and SPAK by WNK1 results in the phosphorylation and activation of NKCC1 (Na+-K+-2Cl- co-transporter 1) for the control of cell volume and blood pressure.
Product Categories/Family for anti-OSR1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
58,022 Da
NCBI Official Full Name
serine/threonine-protein kinase OSR1
NCBI Official Synonym Full Names
oxidative stress responsive 1
NCBI Official Symbol
OXSR1
NCBI Official Synonym Symbols
OSR1
NCBI Protein Information
serine/threonine-protein kinase OSR1; oxidative-stress responsive 1; oxidative stress-responsive 1 protein
UniProt Protein Name
Serine/threonine-protein kinase OSR1
UniProt Gene Name
OXSR1
UniProt Synonym Gene Names
KIAA1101; OSR1
UniProt Entry Name
OXSR1_HUMAN
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Product Notes
The OSR1 oxsr1 (Catalog #AAA211540) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-OSR1 Antibody, Affinity Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's OSR1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IP (Immunoprecipitation). Researchers should empirically determine the suitability of the OSR1 oxsr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OSR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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