IHC (Immunohiostchemistry)
(P2RX7 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the P2RX7 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human, mouse P2RX7 Polyclonal Antibody | anti-P2RX7 antibody
P2RX7 Antibody (C-term)
Gene Names
P2RX7; P2X7
Reactivity
Human, mouse
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
P2RX7, Antibody; P2RX7 Antibody (C-term); P2X purinoceptor 7; P2X7; ATP receptor; P2Z receptor; Purinergic receptor; P2RX7; anti-P2RX7 antibody
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This P2RX7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 563-592 amino acids from the C-terminal region of human P2RX7.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
563-592
Sequence Length
505
Applicable Applications for anti-P2RX7 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(P2RX7 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the P2RX7 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(P2RX7 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the P2RX7 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(P2RX7 Antibody (C-term) western blot analysis in MDA-MB435 cell line and mouse kidney tissue lysates (15ug/lane).This demonstrates the P2RX7 antibody detected the P2RX7 protein (arrow).)
WB (Western Blot)
(P2RX7 Antibody (C-term) western blot analysis in MDA-MB435 cell line and mouse kidney tissue lysates (15ug/lane).This demonstrates the P2RX7 antibody detected the P2RX7 protein (arrow).)
Related Product Information for anti-P2RX7 antibody
P2RX7 belongs to the family of
purinoceptors for ATP. This receptor functions as a ligand-gated
ion channel and is responsible for ATP-dependent lysis of
macrophages through the formation of membrane pores permeable to
large molecules. Activation of this nuclear receptor by ATP in the
cytoplasm may be a mechanism by which cellular activity can be
coupled to changes in gene expression.
purinoceptors for ATP. This receptor functions as a ligand-gated
ion channel and is responsible for ATP-dependent lysis of
macrophages through the formation of membrane pores permeable to
large molecules. Activation of this nuclear receptor by ATP in the
cytoplasm may be a mechanism by which cellular activity can be
coupled to changes in gene expression.
Product Categories/Family for anti-P2RX7 antibody
References
Kim, M., et al. EMBO J. 20(22):6347-6358(2001)
Gartland, A., et al. J. Bone Miner. Res. 16(5):846-856(2001)
Gu, B.J., et al. J. Biol. Chem. 276(14):11135-11142(2001)
Buell, G.N., et al. Recept. Channels 5(6):347-354(1998)
Rassendren, F., et al. J. Biol. Chem. 272(9):5482-5486(1997)
Gartland, A., et al. J. Bone Miner. Res. 16(5):846-856(2001)
Gu, B.J., et al. J. Biol. Chem. 276(14):11135-11142(2001)
Buell, G.N., et al. Recept. Channels 5(6):347-354(1998)
Rassendren, F., et al. J. Biol. Chem. 272(9):5482-5486(1997)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
68585
NCBI Official Full Name
P2X purinoceptor 7
NCBI Official Synonym Full Names
purinergic receptor P2X, ligand gated ion channel, 7
NCBI Official Symbol
P2RX7
NCBI Official Synonym Symbols
P2X7
NCBI Protein Information
P2X purinoceptor 7
UniProt Protein Name
P2X purinoceptor 7
UniProt Gene Name
P2RX7
UniProt Synonym Gene Names
P2X7
UniProt Entry Name
P2RX7_HUMAN
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Product Notes
The P2RX7 p2rx7 (Catalog #AAA288418) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 563-592. The P2RX7 Antibody (C-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's P2RX7 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the P2RX7 p2rx7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "P2RX7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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