Rabbit p53DINP1 Polyclonal Antibody | anti-TP53INP1 antibody

p53DINP1 Antibody

Cat. Num. AAA39970

• Gene Names: TP53INP1; SIP; Teap; p53DINP1; TP53DINP1; TP53INP1A; TP53INP1B
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
• Purity: p53DINP1 Antibody is affinity chromatography purified via peptide column.
• Synonyms: p53DINP1, Antibody; p53DINP1 Antibody; p53DINP1; SIP; Teap; TP53DINP1; TP53INP1A; TP53INP1B; P53DINP1; Tumor protein p53-inducible nuclear protein 1; Stress-induced protein; tumor protein p53 inducible nuclear protein 1; anti-TP53INP1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: At least two isoforms of p53DINP1 are known to exist; this antibody will detect both isoforms.
• Purity/Purification: p53DINP1 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid; p53DINP1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 240

• Applicable Applications for anti-TP53INP1 antibody: WB (Western Blot), IHC (Immunohistochemistry), IF (Immunofluorescence), ELISA
• Immunogen: p53DINP1 antibody was raised with a synthetic peptide corresponding to 14 amino acids near the amino terminus of human p53DINP1.; The immunogen is located within the first 50 amino acids of p53DINP1.
• Positive Control: 1) Cat. No. MBS151589 - Human Lung Tissue Lysate
• Preparation and Storage: p53DINP1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of p53DINP1 in human liver tissue with p53DINP1 antibody at 5 μg/ml.Green: p53DINP1 antibody (3045)Red: Phylloidin stainingBlue: DAPI staining)

IHC (Immunohiostchemistry)

(Immunohistochemical staining of mouse liver using p53DINP1 antibody at 2 μg/mL.)

WB (Western Blot)

(p53DINP1 Antibody)

Related Product Information for anti-TP53INP1 antibody

p53DINP1 Antibody: Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible gene was identified recently and designated p53DINP1 (for p53-dependent damage-inducible nuclear protein 1) and SIP (for stress induced protein) in human and mouse. A p53DINP1 antisense oligonucleotide inhibits and overexpression of p53DINP1 enhances Ser46 phosphorylation of p53, induction of p53AIP1, and cell death induced by DNA double-strand breaks. p53DINP1 may regulate p53-dependent apoptosis through phosphorylation at Ser46 and induction of p53AIP1. The p53DINP1/SIP gene encodes two proteins of 27 and 18 kDa in human and mouse termed p53DINP1-alpha and p53DINP1-beta or SIP27 and SIP18. p53DINP1/SIP is expressed in many tissues and induced by a variety of stress agents including UV stress, mutagenic stress, heat shock, and oxidative stress.

NCBI and Uniprot Product Information

• NCBI GI #: 61216823
• NCBI GeneID: 94241
• UniProt Accession #: Q96A56; Q969R9; B2RCE5
• Molecular Weight: Predicted: 18, 27 kDa; Observed: 30 kDa
• NCBI Official Full Name: Tumor protein p53-inducible nuclear protein 1
• NCBI Official Synonym Full Names: tumor protein p53 inducible nuclear protein 1
• NCBI Official Symbol: TP53INP1
• NCBI Official Synonym Symbols: SIP; Teap; p53DINP1; TP53DINP1; TP53INP1A; TP53INP1B
• NCBI Protein Information: tumor protein p53-inducible nuclear protein 1; p53-inducible p53DINP1; stress-induced protein; p53-dependent damage-inducible nuclear protein 1
• UniProt Protein Name: Tumor protein p53-inducible nuclear protein 1
• UniProt Gene Name: TP53INP1
• UniProt Synonym Gene Names: P53DINP1; SIP; p53DINP1
• UniProt Entry Name: T53I1_HUMAN