IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human brain tissue using at dilution 1/50.)
Rabbit anti-Human TP53INP1 Polyclonal Antibody | anti-TP53INP1 antibody
TP53INP1 Antibody
Gene Names
TP53INP1; SIP; Teap; p53DINP1; TP53DINP1; TP53INP1A; TP53INP1B
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Antigen affinity purification.
Synonyms
TP53INP1, Antibody; TP53INP1 Antibody; SIP; Teap; p53DINP1; TP53DINP1; TP53INP1A; TP53INP1B; anti-TP53INP1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total TP53INP1 protein.
Purity/Purification
Antigen affinity purification.
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Concentration
3 mg/ml (varies by lot)
Sequence Length
164
Applicable Applications for anti-TP53INP1 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide corresponding to residues near the N terminal of human tumor protein p53 inducible nuclear protein 1
Target Name
TP53INP1
Preparation and Storage
Store at -20 degree C
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human brain tissue using at dilution 1/50.)
IHC (Immunohiostchemistry)
(Immunohistochemical analysis of paraffin-embedded Human brain tissue using at dilution 1/50.)
Application Data
(Gel: 10%SDS-PAGE Lysates (from left to right): Human fetal liver tissue, 293T and 231 cell Amount of lysate: 40ug per lane Primary antibody: 1/200 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute)
Application Data
(Gel: 10%SDS-PAGE Lysates (from left to right): Human fetal liver tissue, 293T and 231 cell Amount of lysate: 40ug per lane Primary antibody: 1/200 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute)
Related Product Information for anti-TP53INP1 antibody
TP53INP1 (tumor protein p53-inducible nuclear protein 1), also known as p53DINP1, SIP or Teap, is a 240 amino acid protein that localizes to nuclear bodies and exists as two alternatively spliced isoforms, designated p53DINP1a and p53DINP1b. Expressed ubiquitously with higher expression in testis, pancreas and spleen tissue, TP53INP1 functions in response to double-stranded DNA breaks and regulates p53-mediated apoptosis, specifically by phosphorylating human p53 at Ser 46, an event that leads to cell death. Additionally, TP53INP1 is thought to interact with p73 and may be involved in the regulation of p73-controlled cell cycle progression. TP53INP1 expression is downregulated in pancreatic ductal adenocarcinomas, suggesting that, via its ability to induce cell death, TP53INP1 plays a role in tumor suppression.
Product Categories/Family for anti-TP53INP1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
18,244 Da
NCBI Official Full Name
tumor protein p53-inducible nuclear protein 1 isoform b
NCBI Official Synonym Full Names
tumor protein p53 inducible nuclear protein 1
NCBI Official Symbol
TP53INP1
NCBI Official Synonym Symbols
SIP; Teap; p53DINP1; TP53DINP1; TP53INP1A; TP53INP1B
NCBI Protein Information
tumor protein p53-inducible nuclear protein 1
UniProt Protein Name
Tumor protein p53-inducible nuclear protein 1
UniProt Gene Name
TP53INP1
UniProt Synonym Gene Names
P53DINP1; SIP; p53DINP1
UniProt Entry Name
T53I1_HUMAN
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Product Notes
The TP53INP1 tp53inp1 (Catalog #AAA307521) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TP53INP1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TP53INP1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the TP53INP1 tp53inp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TP53INP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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