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product-image-AAA211704_IP13.jpg IP (Immunoprecipitation) (Detection of human PA1 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-PA1 antibody AAA211704 used for IP at 3 ug/mg lysate. PA1 was also immunoprecipitated by rabbit anti-PA1 antibodies and BL7905, which recognize upstream epitopes. For blotting immunoprecipitated PA1, was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.)

Rabbit anti-Human PA1 Polyclonal Antibody | anti-PA1 antibody

Rabbit anti-PA1 Antibody, Affinity Purified

Gene Names
PAGR1; GAS; PA1; C16orf53
Reactivity
Human
Applications
Immunohistochemistry, Immunoprecipitation
Purity
Antigen Affinity Purified
Synonyms
PA1, Antibody; Rabbit anti-PA1 Antibody, Affinity Purified; PA1; PTIP-associated protein 1; PTIP-associated 1 protein; PAXIP1-associated glutamate-rich protein 1; C16orf53; glutamate-rich coactivator interacting with SRC1; glutamate-rich coactivator associated with SRC1; GAS; glutamate-rich coactivator interacting with SRC1/NCOA1; PAXIP1-associated protein 1; PAXIP1 associated glutamate rich protein 1; anti-PA1 antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Concentration
1000ug/ml (varies by lot)
Applicable Applications for anti-PA1 antibody
IHC (Immunohistochemistry), IP (Immunoprecipitation)
Immunogen
Between 204 and C-terminus
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt

IP (Immunoprecipitation)

(Detection of human PA1 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-PA1 antibody AAA211704 used for IP at 3 ug/mg lysate. PA1 was also immunoprecipitated by rabbit anti-PA1 antibodies and BL7905, which recognize upstream epitopes. For blotting immunoprecipitated PA1, was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.)

product-image-AAA211704_IP13.jpg IP (Immunoprecipitation) (Detection of human PA1 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-PA1 antibody AAA211704 used for IP at 3 ug/mg lysate. PA1 was also immunoprecipitated by rabbit anti-PA1 antibodies and BL7905, which recognize upstream epitopes. For blotting immunoprecipitated PA1, was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.)

IHC (Immunohistochemistry)

(Detection of human PA1 by immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-PA1 (Cat. No. AAA211704 Lot1) used at a dilution of 1:1,000 (1ug/ml). Detection: DAB)

product-image-AAA211704_IHC15.jpg IHC (Immunohistochemistry) (Detection of human PA1 by immunohistochemistry. Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-PA1 (Cat. No. AAA211704 Lot1) used at a dilution of 1:1,000 (1ug/ml). Detection: DAB)
Related Product Information for anti-PA1 antibody
PA1 (PTIP-associated protein 1) was isolated as a protein that associates with PTIP (Pax transactivation domain-interacting protein), a nuclear protein involved in the DNA damage response and interacts with the Pax2 transactivation domain. Along with PTIP, PA1 has been found to be present in a MLL3- and MLL4-containing Histone H3 Lysine 4 Methyltransferase complex. PA1 also appears to be important to the DNA damage response and repair. This involvement in DNA damage signaling is reported to be independent of its MLL association. PA1 has also been identified as GAS (glutamate-rich coactivator interacting with SRC1/NCOA1). As an interactor of SRC1 (steroid receptor coactivator 1), PA1 functions as a transcription cofactor.
Product Categories/Family for anti-PA1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
27,716 Da
NCBI Official Full Name
PAXIP1-associated glutamate-rich protein 1
NCBI Official Synonym Full Names
PAXIP1 associated glutamate-rich protein 1
NCBI Official Symbol
PAGR1
NCBI Official Synonym Symbols
GAS; PA1; C16orf53
NCBI Protein Information
PAXIP1-associated glutamate-rich protein 1; PAXIP1-associated protein 1; PTIP-associated 1 protein; PTIP-associated protein 1; glutamate-rich coactivator associated with SRC1; glutamate-rich coactivator interacting with SRC1/NCOA1
UniProt Protein Name
PAXIP1-associated glutamate-rich protein 1
UniProt Gene Name
PAGR1
UniProt Synonym Gene Names
C16orf53; PA1
UniProt Entry Name
PAGR1_HUMAN

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Product Notes

The PA1 pagr1 (Catalog #AAA211704) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-PA1 Antibody, Affinity Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PA1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IP (Immunoprecipitation). Researchers should empirically determine the suitability of the PA1 pagr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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