Rabbit PAI1 Polyclonal Antibody | anti-PAI1 antibody
PAI1 antibody
Gene Names
SERPINE1; PAI; PAI1; PAI-1; PLANH1
Reactivity
To be determined by end-user.
Applications
Western Blot, ELISA
Synonyms
PAI1, Antibody; PAI1 antibody; Polyclonal PAI1; Anti-PAI1; PAI-1; PAI 1; Plasminogen Activator Inhibitor-1; Serpin E1; PAI1; anti-PAI1 antibody
Host
Rabbit
Reactivity
To be determined by end-user.
Clonality
Polyclonal
Specificity
Human PAL1
Form/Format
Sterile filtered then lyophilized from PBS, pH 7.2.
Concentration
50ug, lyophilized (varies by lot)
Sequence Length
402
Applicable Applications for anti-PAI1 antibody
WB (Western Blot), IA (Inhibition Assay), ELISA
Biological Significance
Plasminogen Activator Inhibitor-1 (PAI-1, Serpin E1) is a member of the serpin family of serine protease inhibitors, and is the primary inhibitor of urokinase and tissue plasminogen activator (tPA). PAI-1 is expressed predominantly in adipose, liver and vascular tissues, and is also produced by certain tumor cells. Elevated levels of PAI-1 are associated with obesity, diabetes and cardiovascular disease, and increased production of PAI-1 is induced by various obesity related factors such as TNFa, glucose, insulin, and very-low-density lipoprotein. The obesity related elevation of PAI-1 levels along with the consequential deficiency in plasminogen activators can lead directly to increased risk of thrombosis and other coronary diseases.
Immunogen
E.coli-derived 42.7 kDa Recombinant Human PAI-1.
Preparation and Storage
Ship ambient or refrigerated. Upon receipt store at 4 degree C short term, -20 degree C to -80 degree C long term. Once reconstituted, avoid repeat freeze-thaws.
Related Product Information for anti-PAI1 antibody
Affinity purified Rabbit polyclonal PAI1 antibody
Product Categories/Family for anti-PAI1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
42.7 kDa (predicted detection band MW)
NCBI Official Full Name
plasminogen activator inhibitor 1
NCBI Official Synonym Full Names
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
NCBI Official Symbol
SERPINE1
NCBI Official Synonym Symbols
PAI; PAI1; PAI-1; PLANH1
NCBI Protein Information
plasminogen activator inhibitor 1
UniProt Protein Name
Plasminogen activator inhibitor 1
UniProt Gene Name
SERPINE1
UniProt Synonym Gene Names
PAI1; PLANH1; PAI; PAI-1
UniProt Entry Name
PAI1_HUMAN
Similar Products
Product Notes
The PAI1 serpine1 (Catalog #AAA75126) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PAI1 antibody reacts with To be determined by end-user. and may cross-react with other species as described in the data sheet. AAA Biotech's PAI1 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IA (Inhibition Assay), ELISA. Researchers should empirically determine the suitability of the PAI1 serpine1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PAI1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.