WB (Western Blot)
(Western blot analysis of extracts from HeLa cells (Lane 2), using PAK3 (Ab-154) antiobdy. The lane on the left is treated with systhesized peptide.)
Rabbit PAK3 Polyclonal Antibody | anti-PAK3 antibody
PAK3 (Ab-154) Antibody
Gene Names
PAK3; bPAK; MRX30; MRX47; OPHN3; PAK-3; PAK3beta; beta-PAK
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
PAK3, Antibody; PAK3 (Ab-154) Antibody; beta-PAK; CDC42/RAC effector kinase PAK-B; EC 2.7.1.; EC 2.7.11.1; kinase PAK3; anti-PAK3 antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total PAK3 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
544
Applicable Applications for anti-PAK3 antibody
WB (Western Blot)
Immunogen Type
Peptide
Immunogen Description
Synthesized non-phosphopeptide derived from human PAK3 around the phosphorylation site of serine 154 (Y-M-S(p)-F-T).
Target Name
PAK3
Preparation and Storage
Store at -20 degree C
WB (Western Blot)
(Western blot analysis of extracts from HeLa cells (Lane 2), using PAK3 (Ab-154) antiobdy. The lane on the left is treated with systhesized peptide.)
WB (Western Blot)
(Western blot analysis of extracts from HeLa cells (Lane 2), using PAK3 (Ab-154) antiobdy. The lane on the left is treated with systhesized peptide.)
WB (Western Blot)
(Western blot analysis of extracts from rat heart, using PAK3 (Ab-154) antibody.)
WB (Western Blot)
(Western blot analysis of extracts from rat heart, using PAK3 (Ab-154) antibody.)
Related Product Information for anti-PAK3 antibody
Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates MAPK4 and MAPK6 and activates the downstream target MAPKAPK5, a regulator of F-actin polymerization and cell migration. Additionally, phosphorylates TNNI3/troponin I to modulate calcium sensitivity and relaxation kinetics of thin myofilaments. May also be involved in early neuronal development.Allen K.M., Nat. Genet. 20:25-30(1998).Jiang C., Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.Kitano T., Mol. Biol. Evol. 20:1281-1289(2003).
Product Categories/Family for anti-PAK3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
62,913 Da
NCBI Official Full Name
serine/threonine-protein kinase PAK 3 isoform a
NCBI Official Synonym Full Names
p21 protein (Cdc42/Rac)-activated kinase 3
NCBI Official Symbol
PAK3
NCBI Official Synonym Symbols
bPAK; MRX30; MRX47; OPHN3; PAK-3; PAK3beta; beta-PAK
NCBI Protein Information
serine/threonine-protein kinase PAK 3
UniProt Protein Name
Serine/threonine-protein kinase PAK 3
UniProt Gene Name
PAK3
UniProt Synonym Gene Names
OPHN3; PAK-3
UniProt Entry Name
PAK3_HUMAN
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Product Notes
The PAK3 pak3 (Catalog #AAA305753) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PAK3 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the PAK3 pak3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PAK3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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