IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PAK7 antibody.)
Rabbit PAK7 Polyclonal Antibody | anti-PAK7 antibody
PAK7 Antibody
Gene Names
PAK7; PAK5
Applications
Immunohistochemistry, Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
PAK7, Antibody; PAK7 Antibody; KIAA1264; p21-activated kinase 7; PAK 7; PAK-5; PAK-7; anti-PAK7 antibody
Host
Rabbit
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total PAK7 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
719
Applicable Applications for anti-PAK7 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from C-terminal of human PAK7.
Target Name
PAK7
Preparation and Storage
Store at -20 degree C
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PAK7 antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PAK7 antibody.)
WB (Western Blot)
(Western blot analysis of extracts from rat brain cells, using PAK7 antibody.)
WB (Western Blot)
(Western blot analysis of extracts from rat brain cells, using PAK7 antibody.)
Related Product Information for anti-PAK7 antibody
Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates the proto-oncogene RAF1 and stimulates its kinase activity. Promotes cell survival by phosphorylating the BCL2 antagonist of cell death BAD. Phosphorylates CTNND1, probably to regulate cytoskeletal organization and cell morphology. Keeps microtubules stable through MARK2 inhibition and destabilizes the F-actin network leading to the disappearance of stress fibers and focal adhesions.Pandey A., Oncogene 21:3939-3948(2002).Nagase T., DNA Res. 6:337-345(1999).Deloukas P., Nature 414:865-871(2001).
Product Categories/Family for anti-PAK7 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
80,745 Da
NCBI Official Full Name
serine/threonine-protein kinase PAK 7
NCBI Official Synonym Full Names
p21 protein (Cdc42/Rac)-activated kinase 7
NCBI Official Symbol
PAK7
NCBI Official Synonym Symbols
PAK5
NCBI Protein Information
serine/threonine-protein kinase PAK 7
UniProt Protein Name
Serine/threonine-protein kinase PAK 7
UniProt Gene Name
PAK7
UniProt Synonym Gene Names
KIAA1264; PAK5; PAK-5; PAK-7
UniProt Entry Name
PAK7_HUMAN
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Product Notes
The PAK7 pak7 (Catalog #AAA306503) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PAK7 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the PAK7 pak7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PAK7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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