WB (Western Blot)
(Detection of human PALB2 by western blot. Samples: Whole cell lysate (50 ug) from HeLa and cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-PALB2 antibody AAA211379 (lot AAA211379-2) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.)
Rabbit anti-Human PALB2 Polyclonal Antibody | anti-PALB2 antibody
Rabbit anti-PALB2 Antibody, Affinity Purified
Gene Names
PALB2; FANCN; PNCA3; FLJ21816; DKFZp667I166; DKFZp686E1054
Reactivity
Human
Applications
Immunohistochemistry, Immunoprecipitation, Western Blot
Purity
Antigen Affinity Purified
Synonyms
PALB2, Antibody; Rabbit anti-PALB2 Antibody, Affinity Purified; FANCN; mutant partner and localizer of BRCA2; partner and localizer of BRCA2; PNCA3; Partner and localizer of BRCA2; anti-PALB2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Concentration
1000ug/ml (varies by lot)
Applicable Applications for anti-PALB2 antibody
IHC (Immunohistochemistry), IP (Immunoprecipitation), WB (Western Blot)
Immunogen
Between 700 and 750
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Shelf Life: 1 year from date of receipt
WB (Western Blot)
(Detection of human PALB2 by western blot. Samples: Whole cell lysate (50 ug) from HeLa and cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-PALB2 antibody AAA211379 (lot AAA211379-2) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.)
WB (Western Blot)
(Detection of human PALB2 by western blot. Samples: Whole cell lysate (50 ug) from HeLa and cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-PALB2 antibody AAA211379 (lot AAA211379-2) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.)
IP (Immunoprecipitation)
(Detection of human PALB2 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from HeLa cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-PALB2 antibody AAA211379 (lot AAA211379-2) used for IP at 6 ug per reaction. PALB2 was also immunoprecipitated by rabbit anti-PALB2 antibody For blotting immunoprecipitated PALB2, AAA211379 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.)
IP (Immunoprecipitation)
(Detection of human PALB2 by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from HeLa cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-PALB2 antibody AAA211379 (lot AAA211379-2) used for IP at 6 ug per reaction. PALB2 was also immunoprecipitated by rabbit anti-PALB2 antibody For blotting immunoprecipitated PALB2, AAA211379 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.)
IHC (Immunohistochemistry)
(Detection of human PALB2 by immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-PALB2 (Cat. No. AAA211379 Lot2) used at a dilution of 1:1,000 (1 ug/ml). Detection: DAB)
IHC (Immunohistochemistry)
(Detection of human PALB2 by immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-PALB2 (Cat. No. AAA211379 Lot2) used at a dilution of 1:1,000 (1 ug/ml). Detection: DAB)
Related Product Information for anti-PALB2 antibody
PALB2 (partner and localizer of BRCA2) interacts with BRCA2 and promotes BRCA2 localization and stability. PALB2 is also known as FANCN. Bi-allelic mutations in PALB2 result in Fanconi anemia disorder and breast cancer susceptibility. At the cellular level, PALB2 is important to the DNA damage response and chromosome stability and is essential to BRCA2 function.
Product Categories/Family for anti-PALB2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
131,295 Da
NCBI Official Full Name
partner and localizer of BRCA2
NCBI Official Synonym Full Names
partner and localizer of BRCA2
NCBI Official Symbol
PALB2
NCBI Official Synonym Symbols
FANCN; PNCA3; FLJ21816; DKFZp667I166; DKFZp686E1054
NCBI Protein Information
partner and localizer of BRCA2
UniProt Protein Name
Partner and localizer of BRCA2
UniProt Gene Name
PALB2
UniProt Synonym Gene Names
FANCN
UniProt Entry Name
PALB2_HUMAN
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Product Notes
The PALB2 palb2 (Catalog #AAA211379) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-PALB2 Antibody, Affinity Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PALB2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), IP (Immunoprecipitation), WB (Western Blot). Researchers should empirically determine the suitability of the PALB2 palb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PALB2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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