IF (Immunofluorescence)
(Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using PCBP2 antibody at 1: 200 dilution.)
Rabbit anti-Human PCBP2 Polyclonal Antibody | anti-PCBP2 antibody
PCBP2 antibody
Gene Names
PCBP2; HNRPE2; HNRNPE2; hnRNP-E2
Reactivity
Human
Applications
Immunofluorescence, Western Blot
Purity
Purified by antigen-affinity chromatography.
Synonyms
PCBP2, Antibody; PCBP2 antibody; HNRPE2; MGC110998; hnRNP-E2; anti-PCBP2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Purified by antigen-affinity chromatography.
Form/Format
Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Sequence Length
362
Applicable Applications for anti-PCBP2 antibody
IF (Immunofluorescence), WB (Western Blot)
Immunogen Type
Peptide
Immunogen Description
Synthetic peptide contain a sequence corresponding to a region within amino acids 299 and 362 of PCBP2
Target Name
PCBP2
Preparation and Storage
Store at -20 degree C for long term preservation (recommended). Store at 4 degree C for short term use.
IF (Immunofluorescence)
(Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using PCBP2 antibody at 1: 200 dilution.)
IF (Immunofluorescence)
(Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using PCBP2 antibody at 1: 200 dilution.)
Application Data
(Sample (30 ug of whole cell lysate) A: Hep G2 10% SDS PAGE Primary antibody diluted at 1: 500)
Application Data
(Sample (30 ug of whole cell lysate) A: Hep G2 10% SDS PAGE Primary antibody diluted at 1: 500)
Related Product Information for anti-PCBP2 antibody
The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly(rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate PCBP-1, an intronless gene with functions similar to that of PCBP2. This gene and PCBP-1 have paralogous genes (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. Thsi gene also has two processed pseudogenes (PCBP2P1 and PCBP2P2). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Product Categories/Family for anti-PCBP2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
33,926 Da
NCBI Official Full Name
poly(rC)-binding protein 2 isoform b
NCBI Official Synonym Full Names
poly(rC) binding protein 2
NCBI Official Symbol
PCBP2
NCBI Official Synonym Symbols
HNRPE2; HNRNPE2; hnRNP-E2
NCBI Protein Information
poly(rC)-binding protein 2
UniProt Protein Name
Poly(rC)-binding protein 2
UniProt Gene Name
PCBP2
UniProt Synonym Gene Names
hnRNP E2
UniProt Entry Name
PCBP2_HUMAN
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Product Notes
The PCBP2 pcbp2 (Catalog #AAA305453) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PCBP2 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PCBP2 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot). Researchers should empirically determine the suitability of the PCBP2 pcbp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PCBP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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