IHC (Immunohistochemisry)
Rabbit PDE11A Polyclonal Antibody | anti-PDE11A antibody
PDE11A Antibody
Gene Names
PDE11A; PPNAD2
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunoprecipitation, Immunohistochemistry, Immunofluorescence, Immunocytochemistry, ELISA
Synonyms
PDE11A, Antibody; PDE11A Antibody; 5''-cyclic-AMP and -GMP phosphodiesterase 11A; cAMP and cGMP cyclic nucleotide phosphodiesterase 11A; Cyclic nucleotide phosphodiesterase 11A1; Dual 3' 5' cyclic AMP and GMP phosphodiesterase 11A; FLJ23693; MGC133355; MGC133356; PDE 11A; pde11; pde11a2; Phosphodiesterase 11A; PPNAD2 antibody; anti-PDE11A antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
This antibody does not cross-react with any of the members of the PDE family. This antibody is common to all PDE11A variants including PDE11A1-PDE11A4.
Form/Format
Affinity Purified
Concentration
0.68 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
490
Applicable Applications for anti-PDE11A antibody
WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry), IF (Immunofluorescence), ICC (Immunocytochemistry), ELISA, CM (Confocal Microscopy)
Immunogen
Synthetic peptide taken within amino acid region 100-150 on PDE11A protein, common to all PDE11A variants.
Expression
Isoform 1 is present in prostate, pituitary, heart and liver. It is however not present in testis nor in penis, suggesting that weak inhibition by Tadalafil is not relevant (at protein level). Isoform 2 may be expressed in testis. Isoform 4 is expressed i
Determinant
N-epitope
Molecular Function
Hydrolase, metal-ion binding, cGMP binding
Subcellular Location
Cytoplasm
Preparation and Storage
-20 degree C for long term storage
IHC (Immunohistochemisry)
IHC (Immunohistochemisry)
WB (Western Blot)
WB (Western Blot)
WB (Western Blot)
WB (Western Blot)
Related Product Information for anti-PDE11A antibody
Affinity Purified Cyclic Nucleotide Phosphodiesterase 11A1 Antibody N-epitope
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively.
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively.
Product Categories/Family for anti-PDE11A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
55,700 Da
NCBI Official Full Name
cyclic nucleotide phosphodiesterase 11A1
NCBI Official Synonym Full Names
phosphodiesterase 11A
NCBI Official Symbol
PDE11A
NCBI Official Synonym Symbols
PPNAD2
NCBI Protein Information
dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
UniProt Protein Name
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
UniProt Gene Name
PDE11A
UniProt Entry Name
PDE11_HUMAN
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Product Notes
The PDE11A pde11a (Catalog #AAA75995) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PDE11A Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PDE11A can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry), IF (Immunofluorescence), ICC (Immunocytochemistry), ELISA, CM (Confocal Microscopy). Researchers should empirically determine the suitability of the PDE11A pde11a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDE11A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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