Application Data
Rabbit PDE5A Polyclonal Antibody | anti-PDE5A antibody
PDE5A Antibody
Gene Names
PDE5A; CN5A; PDE5; CGB-PDE
Reactivity
Human, Mouse, Pig, Rat
Applications
Western Blot, Immunoprecipitation, Immunohistochemistry, Immunofluorescence, Immunocytochemistry, ELISA
Synonyms
PDE5A, Antibody; PDE5A Antibody; 5''-cyclic phosphodiesterase; CGB PDE; cGMP binding cGMP specific 3' 5' cyclic nucleotide phosphodiesterase; cGMP binding/cGMP specific phosphodiesterase; cGMP specific 3'5' cyclic phosphodiesterase; cGMP specific phosphodiesterase PDE5A2; cGMP specific phosphodiesterase type 5A; cGMP-specific 3''; CN5A; CN5N; PDE 5; PDE 5A; PDE5A1; Phosphodiesterase 5A; Phosphodiesterase 5A cGMP specific; Phosphodiesterase isozyme 5 antibody; anti-PDE5A antibody
Host
Rabbit
Reactivity
Human, Mouse, Pig, Rat
Clonality
Polyclonal
Specificity
This antibody detects 99 and 89 kDa PDE5A proteins in various tissues. This antibody does not cross-react with other PDE family members.
Form/Format
Affinity Purified
Concentration
0.55-0.60 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
875
Applicable Applications for anti-PDE5A antibody
WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry), IF (Immunofluorescence), ICC (Immunocytochemistry), ELISA, CM (Confocal Microscopy)
Immunogen
Synthetic peptide common to all PDE5A variants taken within amino acid region 120-170 on human PDE5A protein.
Expression
Expressed in aortic smooth muscle cells, heart, placenta, skeletal muscle and pancreas and, to a much lesser extent, in brain, liver and lung.
Molecular Function
Hydrolase, 3', 5'-cyclic-GMP phosphodiesterase activity, cGMP binding
Subcellular Location
Cytosol
Preparation and Storage
-20 degree C for long term storage
Application Data
Application Data
WB (Western Blot)
WB (Western Blot)
Related Product Information for anti-PDE5A antibody
Affinity Purified cGMP-specific 3', 5'-cyclic phosphodiesterase isoform 1 Antibody
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP.
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP.
Product Categories/Family for anti-PDE5A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
94,805 Da
NCBI Official Full Name
cGMP-specific 3',5'-cyclic phosphodiesterase
NCBI Official Synonym Full Names
phosphodiesterase 5A
NCBI Official Symbol
PDE5A
NCBI Official Synonym Symbols
CN5A; PDE5; CGB-PDE
NCBI Protein Information
cGMP-specific 3',5'-cyclic phosphodiesterase
UniProt Protein Name
cGMP-specific 3',5'-cyclic phosphodiesterase
UniProt Gene Name
PDE5A
UniProt Synonym Gene Names
PDE5; CGB-PDE
UniProt Entry Name
PDE5A_HUMAN
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Product Notes
The PDE5A pde5a (Catalog #AAA75647) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PDE5A Antibody reacts with Human, Mouse, Pig, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PDE5A can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry), IF (Immunofluorescence), ICC (Immunocytochemistry), ELISA, CM (Confocal Microscopy). Researchers should empirically determine the suitability of the PDE5A pde5a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDE5A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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