IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded mouse retina using PDE6B antibody (AAA280067) at dilution of 1:200 (40x lens).)
Rabbit PDE6B Polyclonal Antibody | anti-PDE6B antibody
PDE6B
Gene Names
PDE6B; rd1; PDEB; RP40; CSNB3; CSNBAD2
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot
Purity
Affinity purification
Synonyms
PDE6B, Antibody; PDE6B; anti-PDE6B antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.
Sequence Length
854
Applicable Applications for anti-PDE6B antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot)
Species
Human
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human PDE6B (NB_001138763.1).
IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded mouse retina using PDE6B antibody (AAA280067) at dilution of 1:200 (40x lens).)
IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded mouse retina using PDE6B antibody (AAA280067) at dilution of 1:200 (40x lens).)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded rat retina using PDE6B antibody (AAA280067) at dilution of 1:200 (40x lens).)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded rat retina using PDE6B antibody (AAA280067) at dilution of 1:200 (40x lens).)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using PDE6B antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines, using PDE6B antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit.Exposure time: 90s.)
Related Product Information for anti-PDE6B antibody
Photon absorption triggers a signaling cascade in rod photoreceptors that activates cGMP phosphodiesterase (PDE), resulting in the rapid hydrolysis of cGMP, closure of cGMP-gated cation channels, and hyperpolarization of the cell. PDE is a peripheral membrane heterotrimeric enzyme made up of alpha, beta, and gamma subunits. This gene encodes the beta subunit. Mutations in this gene result in retinitis pigmentosa and autosomal dominant congenital stationary night blindness. Multiple transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-PDE6B antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
Observed MW: 98 kDa
Calculated MW: 66 kDa/98 kDa
Calculated MW: 66 kDa/98 kDa
NCBI Official Full Name
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
NCBI Official Synonym Full Names
phosphodiesterase 6B, cGMP-specific, rod, beta
NCBI Official Symbol
PDE6B
NCBI Official Synonym Symbols
rd1; PDEB; RP40; CSNB3; CSNBAD2
NCBI Protein Information
rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta; GMP-PDE beta; rod cGMP-phosphodiesterase beta-subunit
UniProt Protein Name
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta
UniProt Gene Name
PDE6B
UniProt Synonym Gene Names
PDEB; GMP-PDE beta
UniProt Entry Name
PDE6B_HUMAN
Similar Products
Product Notes
The PDE6B pde6b (Catalog #AAA280067) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PDE6B reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PDE6B can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the PDE6B pde6b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PDE6B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.