Rabbit PEAR1 Polyclonal Antibody | anti-PEAR1 antibody

PEAR1 Antibody

Cat. Num. AAA40246

• Gene Names: PEAR1; JEDI; MEGF12
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: PEAR1 Antibody is affinity chromatography purified via peptide column.
• Synonyms: PEAR1, Antibody; PEAR1 Antibody; PEAR1; JEDI; MEGF12; Platelet endothelial aggregation receptor 1; Multiple epidermal growth factor-like domains protein 12; hPEAR1; platelet endothelial aggregation receptor 1; anti-PEAR1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: PEAR1 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 1037

• Applicable Applications for anti-PEAR1 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: PEAR1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human PEAR1.
• Buffer: PEAR1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: PEAR1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of PEAR1 in human kidney tissue with PEAR1 antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of PEAR1 in human kidney tissue with PEAR1 antibody at 2.5 μg/mL.)

WB (Western Blot)

(Western blot analysis of PEAR1 in rat kidney tissue lysate with PEAR1 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)

Related Product Information for anti-PEAR1 antibody

PEAR1 Antibody: Platelet endothelial aggregation receptor 1 (PEAR1) is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation. Upon platelet aggregation stimulated by physiological agonists, PEAR1 becomes tyrosine- and serine-phosphorylated; the tyrosine phosphorylation can be inhibited by eptifibatide, an aIIbbeta3 antagonist that also inhibits platelet aggregation. Recent studies have indicated that genetic variations in PEAR1, may be associated with enhanced agonist-induced platelet aggregation.

NCBI and Uniprot Product Information

• NCBI GI #: 122937343
• NCBI GeneID: 375033
• NCBI Accession #: NP_001073940
• NCBI GenBank Nucleotide #: NM_001080471.1
• UniProt Accession #: Q5VY43; Q8TEK2
• Molecular Weight: 110,666 Da
• NCBI Official Full Name: platelet endothelial aggregation receptor 1
• NCBI Official Synonym Full Names: platelet endothelial aggregation receptor 1
• NCBI Official Symbol: PEAR1
• NCBI Official Synonym Symbols: JEDI; MEGF12
• NCBI Protein Information: platelet endothelial aggregation receptor 1; hPEAR1; multiple EGF-like-domains 12; multiple EGF-like domains protein 12; multiple epidermal growth factor-like domains protein 12
• UniProt Protein Name: Platelet endothelial aggregation receptor 1
• UniProt Gene Name: PEAR1
• UniProt Synonym Gene Names: MEGF12; hPEAR1; Multiple EGF-like domains protein 12
• UniProt Entry Name: PEAR1_HUMAN