IHC (Immunohiostchemistry)
(PEAR1 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PEAR1 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human PEAR1 Polyclonal Antibody | anti-PEAR1 antibody
PEAR1 Antibody (C-term)
Gene Names
PEAR1; JEDI; MEGF12
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
PEAR1, Antibody; PEAR1 Antibody (C-term); Platelet endothelial aggregation receptor 1; hPEAR1; Multiple epidermal growth factor-like domains protein 12; Multiple EGF-like domains protein 12; PEAR1; MEGF12; anti-PEAR1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This PEAR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 961-990 amino acids from the C-terminal region of human PEAR1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
961-990
Sequence Length
1037
Applicable Applications for anti-PEAR1 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(PEAR1 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PEAR1 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(PEAR1 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PEAR1 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(PEAR1 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the PEAR1 antibody detected the PEAR1 protein (arrow).)
WB (Western Blot)
(PEAR1 Antibody (C-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the PEAR1 antibody detected the PEAR1 protein (arrow).)
Related Product Information for anti-PEAR1 antibody
PEAR1 is a platelet receptor that signals upon the
formation of platelet-platelet contacts independent of platelet
activation and secondary to platelet aggregation (Nanda et al.,
2005 [PubMed 15851471]).
formation of platelet-platelet contacts independent of platelet
activation and secondary to platelet aggregation (Nanda et al.,
2005 [PubMed 15851471]).
Product Categories/Family for anti-PEAR1 antibody
References
Johnson, A.D., et al. Nat. Genet. 42(7):608-613(2010)
Jones, C.I., et al. Blood 114(7):1405-1416(2009)
Herrera-Galeano, J.E., et al. Arterioscler. Thromb. Vasc. Biol. 28(8):1484-1490(2008)
Nanda, N., et al. J. Biol. Chem. 280(26):24680-24689(2005)
Nanda, N., et al. J. Biol. Chem. 280(26):24680-24689(2005)
Jones, C.I., et al. Blood 114(7):1405-1416(2009)
Herrera-Galeano, J.E., et al. Arterioscler. Thromb. Vasc. Biol. 28(8):1484-1490(2008)
Nanda, N., et al. J. Biol. Chem. 280(26):24680-24689(2005)
Nanda, N., et al. J. Biol. Chem. 280(26):24680-24689(2005)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
110666
NCBI Official Full Name
platelet endothelial aggregation receptor 1
NCBI Official Synonym Full Names
platelet endothelial aggregation receptor 1
NCBI Official Symbol
PEAR1
NCBI Official Synonym Symbols
JEDI; MEGF12
NCBI Protein Information
platelet endothelial aggregation receptor 1
UniProt Protein Name
Platelet endothelial aggregation receptor 1
UniProt Gene Name
PEAR1
UniProt Synonym Gene Names
MEGF12; hPEAR1; Multiple EGF-like domains protein 12
UniProt Entry Name
PEAR1_HUMAN
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Product Notes
The PEAR1 pear1 (Catalog #AAA288122) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 961-990. The PEAR1 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PEAR1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the PEAR1 pear1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PEAR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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