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product-image-AAA173705_IF11.jpg IF (Immunofluorescence) (Immunofluorescence analysis of Rat spleen tissue using PERK Polyclonal Antibody at dilution of 1:200.)

Rabbit PERK Polyclonal Antibody | anti-PERK antibody

PERK Polyclonal Antibody

Gene Names
EIF2AK3; PEK; WRS; PERK
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunofluorescence, Immunohistochemistry
Purity
Affinity Purification
Synonyms
PERK, Antibody; PERK Polyclonal Antibody; EIF2AK3; PEK; PERK; Eukaryotic translation initiation factor 2-alpha kinase 3; PRKR-like endoplasmic reticulum kinase; Pancreatic eIF2-alpha kinase; HsPEK; anti-PERK antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity Purification
Concentration
1mg/mL (varies by lot)
Sequence Length
1116
Applicable Applications for anti-PERK antibody
ELISA, IF (Immunofluorescence), IHC (Immunohistochemistry)
Immunogen
Synthesized peptide derived from human PERK around the non-phosphorylation site of Thr981.
Buffer
PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.

IF (Immunofluorescence)

(Immunofluorescence analysis of Rat spleen tissue using PERK Polyclonal Antibody at dilution of 1:200.)

product-image-AAA173705_IF11.jpg IF (Immunofluorescence) (Immunofluorescence analysis of Rat spleen tissue using PERK Polyclonal Antibody at dilution of 1:200.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded Human stomach cancer tissue using PERK Polyclonal Antibody at dilution of 1:200.)

product-image-AAA173705_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of paraffin-embedded Human stomach cancer tissue using PERK Polyclonal Antibody at dilution of 1:200.)

IHC (Immunohistochemistry)

(Immunohistochemistry of paraffin-embedded Human stomach tissue using PERK Polyclonal Antibody at dilution of 1:200.)

product-image-AAA173705_IHC15.jpg IHC (Immunohistochemistry) (Immunohistochemistry of paraffin-embedded Human stomach tissue using PERK Polyclonal Antibody at dilution of 1:200.)
Related Product Information for anti-PERK antibody
Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin D1.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Calculated Molecular Weight: 125kDa
Observed Molecular Weight: 125kDa
NCBI Official Full Name
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 2 alpha kinase 3
NCBI Official Symbol
EIF2AK3
NCBI Official Synonym Symbols
PEK; WRS; PERK
NCBI Protein Information
eukaryotic translation initiation factor 2-alpha kinase 3
UniProt Protein Name
Eukaryotic translation initiation factor 2-alpha kinase 3
UniProt Gene Name
EIF2AK3
UniProt Synonym Gene Names
PEK; PERK; HsPEK

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Product Notes

The PERK eif2ak3 (Catalog #AAA173705) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PERK Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PERK can be used in a range of immunoassay formats including, but not limited to, ELISA, IF (Immunofluorescence), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the PERK eif2ak3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PERK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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