Rabbit PHOX2A Polyclonal Antibody | anti-PHOX2A antibody

PHOX2A Antibody

Cat. Num. AAA39736

• Gene Names: PHOX2A; ARIX; FEOM2; NCAM2; PMX2A; CFEOM2
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: PHOX2A Antibody is affinity chromatography purified via peptide column.
• Synonyms: PHOX2A, Antibody; PHOX2A Antibody; PHOX2A; ARIX; FEOM2; NCAM2; PMX2A; CFEOM2; Paired mesoderm homeobox protein 2A; ARIX1 homeodomain protein; paired-like homeobox 2a; anti-PHOX2A antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: PHOX2A antibody is predicted to not cross-react with other paired homeobox family members.
• Purity/Purification: PHOX2A Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 284

• Applicable Applications for anti-PHOX2A antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: PHOX2A antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human PHOX2A.
• Buffer: PHOX2A Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: PHOX2A antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of PHOX2A in human brain tissue with PHOX2A antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of PHOX2A in human brain tissue with PHOX2A antibody at 2.5 μg/mL.)

WB (Western Blot)

(Western blot analysis of PHOX2A in rat brain tissue lysate with PHOX2A antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide.)

Related Product Information for anti-PHOX2A antibody

PHOX2A Antibody: PHOX2A and PHOX2B (Paired mesoderm homeobox protein) are closely related, paired-homeodomain transcription factors that function as determinants of the noradrenergic phenotype during embryogenesis. PHOX2 proteins are crucial for the regulation of endogenous hydroxylases in neural crest cells and promote sympathetic neuron generation. Human PHOX2B contains one DNA binding homeobox domain and is required for the differentiation of all central and nonperipheral noradrenergic centers in the brain. In contrast, PHOX2A controls only the differentiation of the main noradrenergic center of the brain. Regulation of PHOX2 may have therapeutic utility in aging or disorders involving degeneration of noradrenergic neurons.

NCBI and Uniprot Product Information

• NCBI GI #: 46249382
• NCBI GeneID: 401
• NCBI Accession #: NP_005160
• NCBI GenBank Nucleotide #: NM_005169.3
• UniProt Accession #: O14813; Q8IVZ2; A8K3N0
• Molecular Weight: 29,653 Da
• NCBI Official Full Name: paired mesoderm homeobox protein 2A
• NCBI Official Synonym Full Names: paired-like homeobox 2a
• NCBI Official Symbol: PHOX2A
• NCBI Official Synonym Symbols: ARIX; FEOM2; NCAM2; PMX2A; CFEOM2
• NCBI Protein Information: paired mesoderm homeobox protein 2A; arix homeodomain protein; ARIX1 homeodomain protein; aristaless homeobox homolog; aristaless homeobox protein homolog
• UniProt Protein Name: Paired mesoderm homeobox protein 2A
• UniProt Gene Name: PHOX2A
• UniProt Synonym Gene Names: ARIX; PMX2A
• UniProt Entry Name: PHX2A_HUMAN