Rabbit anti-Human, Mouse PIK3R3 Polyclonal Antibody | anti-PIK3R3 antibody

PIK3R3 Antibody

Cat. Num. AAA304595

• Gene Names: PIK3R3; p55; p55PIK; p55-GAMMA
• Reactivity: Human, Mouse
• Applications: Immunohistochemistry, Western Blot
• Purity: Antigen affinity purification.
• Synonyms: PIK3R3, Antibody; PIK3R3 Antibody; p55; p55-GAMMA; anti-PIK3R3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Specificity: The antibody detects endogenous levels of total PIK3R3 protein.
• Purity/Purification: Antigen affinity purification.
• Form/Format: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 461

• Applicable Applications for anti-PIK3R3 antibody: IHC (Immunohistochemistry), WB (Western Blot)
• Immunogen Type: Peptide
• Immunogen Description: Synthetic peptide corresponding to a region derived from internal residues of human phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
• Target Name: PIK3R3
• Preparation and Storage: Store at -20 degree C

IHC (Immunohiostchemistry)

(Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using at dilution 1/25.)

Application Data

(Gel: 10%SDS-PAGE Lysates (from left to right): Mouse brain, human fetal brain and mouse testis tissue, hela cell and human fetal kidney tissue Amount of lysate: 40ug per lane Primary antibody: 1/250 dilution Secondary antibody dilution: 1/8000 Exposure time: 2 minutes)

Related Product Information for anti-PIK3R3 antibody

Phosphatidylinositol 3-kinase is a lipid kinase that phosphorylates the inositol ring of phosphatidylinositol and related compounds at the 3¡¯ position. PI 3-kinase p55 (PIK3R3) is comprised of a catalytic subunit and a regulatory subunit. The human p55 protein is composed of a rare amino terminal region followed by a proline-rich motif and two Src homology 2 (SH2) domains. PI 3-kinase p55 mRNAs are expressed in most human fetal and adult tissues; predominant expression is observed in the adult testis. Splice variant(s) of PI 3-kinase p55 have been identified; one of which has a deletion of 36 amino acids at the amino terminus and another which has an insertion of 59 amino acids at position 256 between the SH2 domains. Research suggests that PI 3-kinase p55 interacts with the IGFIR (Insulin-like growth factor-I receptor) and IR (Insulin receptor) and may be involved in PI 3-kinase activation by these receptors.

Product Categories/Family for anti-PIK3R3 antibody

Total protein Ab

NCBI and Uniprot Product Information

• NCBI GI #: 166795247
• NCBI GeneID: 8503
• NCBI Accession #: NP_001107644.1
• NCBI GenBank Nucleotide #: NM_001114172.1
• UniProt Accession #: Q92569; O60482; Q5T4P1; Q5T4P2; B2R9C1; D3DQ12
• Molecular Weight: 43,465 Da
• NCBI Official Full Name: phosphatidylinositol 3-kinase regulatory subunit gamma
• NCBI Official Synonym Full Names: phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
• NCBI Official Symbol: PIK3R3
• NCBI Official Synonym Symbols: p55; p55PIK; p55-GAMMA
• NCBI Protein Information: phosphatidylinositol 3-kinase regulatory subunit gamma
• UniProt Protein Name: Phosphatidylinositol 3-kinase regulatory subunit gamma
• UniProt Gene Name: PIK3R3
• UniProt Synonym Gene Names: PI3-kinase regulatory subunit gamma; PI3K regulatory subunit gamma; PtdIns-3-kinase regulatory subunit gamma; PI3-kinase subunit p55-gamma; PtdIns-3-kinase regulatory subunit p55-gamma
• UniProt Entry Name: P55G_HUMAN