IF (Immunofluorescence)
(Immunofluorescence of PINK1 in mouse brain tissue with PINK1 Antibody at 20 μg/mL.Green: PINK1 antibody (7859)Red: Phylloidin stainingBlue: DAPI staining)
Rabbit PINK1 Polyclonal Antibody | anti-PINK1 antibody
PINK1 Antibody
Gene Names
PINK1; BRPK; PARK6
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
PINK1 antibody is affinity chromatography purified via peptide column.
Synonyms
PINK1, Antibody; PINK1 Antibody; PINK1; BRPK; PARK6BRPK; PTEN induced putative kinase 1; anti-PINK1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
PINK1 antibody is human, mouse and rat reactive. At least two isoforms are known to exist; this antibody will only detect the longer isoform. PINK1 antibody will detect the cleaved and uncleaved form of PINK1.
Purity/Purification
PINK1 antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
581
Applicable Applications for anti-PINK1 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
PINK1 antibody was raised against a 16 amino acid peptide near the amino terminus of human PINK1.
Buffer
PINK1 antibody is supplied in PBS containing 0.02% sodium azide.
The immunogen is located within amino acids 120 - 170 of PINK1.
The immunogen is located within amino acids 120 - 170 of PINK1.
Positive Control
1) - A431 Cell Lysate
2) - Mouse Spleen Tissue Lysate
3) - Rat Spleen Tissue Lysate
2) - Mouse Spleen Tissue Lysate
3) - Rat Spleen Tissue Lysate
Preparation and Storage
PINK1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.
IF (Immunofluorescence)
(Immunofluorescence of PINK1 in mouse brain tissue with PINK1 Antibody at 20 μg/mL.Green: PINK1 antibody (7859)Red: Phylloidin stainingBlue: DAPI staining)
IF (Immunofluorescence)
(Immunofluorescence of PINK1 in mouse brain tissue with PINK1 Antibody at 20 μg/mL.Green: PINK1 antibody (7859)Red: Phylloidin stainingBlue: DAPI staining)
IHC (Immunohiostchemistry)
(Immunohistochemistry of PINK1 in mouse brain tissue with PINK1 Antibody at 5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of PINK1 in mouse brain tissue with PINK1 Antibody at 5 μg/mL.)
WB (Western Blot)
WB (Western Blot)
Related Product Information for anti-PINK1 antibody
The PTEN-induced putative kinase 1 (PINK1) is a serine/threonine protein kinase that localizes to mitochondria and is thought to protect cells from stress-induced mitochondrial dysfunction (reviewed in 1). PINK1 recruits the E3 ubiquitin ligase Parkin to mitochondria to initiate mitophagy, an autophagic process that clears damaged mitochondria within a cell (2). PINK1 is cleaved by the mitochondrial protease PARL (3). Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease (4).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 55 kDa
Observed: 53 kDa
Observed: 53 kDa
NCBI Official Full Name
serine/threonine-protein kinase PINK1, mitochondrial
NCBI Official Synonym Full Names
PTEN induced putative kinase 1
NCBI Official Symbol
PINK1
NCBI Official Synonym Symbols
BRPK; PARK6
NCBI Protein Information
serine/threonine-protein kinase PINK1, mitochondrial; protein kinase BRPK; PTEN-induced putative kinase protein 1
UniProt Protein Name
Serine/threonine-protein kinase PINK1, mitochondrial
UniProt Gene Name
PINK1
UniProt Entry Name
PINK1_HUMAN
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Product Notes
The PINK1 pink1 (Catalog #AAA40652) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PINK1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PINK1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the PINK1 pink1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PINK1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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