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product-image-AAA304114_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of POLR3F in human brain tissue with POLR3F antibody at 2.5 ug/mL.)

Rabbit POLR3F Polyclonal Antibody | anti-POLR3F antibody

POLR3F Antibody

Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
POLR3F, Antibody; POLR3F Antibody; RNA polymerase III polypeptide F, RNA polymerase subunit C6, RPC6, RPC39; anti-POLR3F antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
316
Applicable Applications for anti-POLR3F antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 21 amino acid peptide from near the amino terminus of human POLR3F.
Target Name
POLR3F
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IHC (Immunohiostchemistry)

(Immunohistochemistry of POLR3F in human brain tissue with POLR3F antibody at 2.5 ug/mL.)

product-image-AAA304114_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of POLR3F in human brain tissue with POLR3F antibody at 2.5 ug/mL.)

WB (Western Blot)

(Western blot analysis of POLR3F in human brain tissue lysate with POLR3F antibody at (A) 0.5 and (B) 1 ug/mL.)

product-image-AAA304114_WB15.gif WB (Western Blot) (Western blot analysis of POLR3F in human brain tissue lysate with POLR3F antibody at (A) 0.5 and (B) 1 ug/mL.)
Related Product Information for anti-POLR3F antibody
The human POLR3F is a component of RNA III polymerase. RNA polymerase III transcribes many essential, small, noncoding RNAs, including the 5S rRNAs and tRNAs. While most pol III-transcribed genes are found scattered throughout the linear chromosome maps or in multiple linear clusters, there is increasing evidence that many of these genes prefer to be spatially clustered, often at or near the nucleolus. This association could create an environment that fosters the coregulation of transcription by pol III with transcription of the large ribosomal RNA repeats by RNA polymerase I (pol I) within the nucleolus. Given the high number of pol III-transcribed genes in all eukaryotic genomes, the spatial organization of these genes is likely to affect a large portion of the other genes in a genome. POLR3F has also been recently identified as an HIV dependency factor (HDF), suggesting that POLR3F may be an important drug target in HIV treatment. At least two isoforms of POLR3F are known to exist.
Product Categories/Family for anti-POLR3F antibody

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
35,684 Da
UniProt Protein Name
DNA-directed RNA polymerase III subunit RPC6
UniProt Gene Name
POLR3F
UniProt Synonym Gene Names
RNA polymerase III subunit C6; RPC39
UniProt Entry Name
RPC6_HUMAN

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Product Notes

The POLR3F polr3f (Catalog #AAA304114) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The POLR3F Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's POLR3F can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the POLR3F polr3f for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "POLR3F, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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