WB (Western Blot)
(The anti-PPP6C Pab is used in Western blot to detect PPP6C in Thymus cell lysate.)
Rabbit anti-Human PPP6C Polyclonal Antibody | anti-PPP6C antibody
PPP6C Antibody (N-term)
Gene Names
PPP6C; PP6; PP6C
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
PPP6C, Antibody; PPP6C Antibody (N-term); Serine/threonine-protein phosphatase 6 catalytic subunit; PP6C; N-terminally processed; PPP6C; PPP6; anti-PPP6C antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This PPP6C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PPP6C.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
1-30
Sequence Length
342
Applicable Applications for anti-PPP6C antibody
WB (Western Blot), IHC (Immunohistochemistry), ELISA
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(The anti-PPP6C Pab is used in Western blot to detect PPP6C in Thymus cell lysate.)
WB (Western Blot)
(The anti-PPP6C Pab is used in Western blot to detect PPP6C in Thymus cell lysate.)
IHC (Immunohistochemistry)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
IHC (Immunohistochemistry)
(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
Related Product Information for anti-PPP6C antibody
PPP6C belongs to the PPP phosphatase family, PP-V subfamily. Reversible phosphorylation of proteins on serine and threonine residues is an important biochemical event that regulates a broad variety of intracellular processes. The phosphorylation state is determined by the well-controlled balance of activities of serine/threonine-specific protein kinases and protein phosphatases, including PPP6C. Expression levels are highest in testis, heart, and skeletal muscle and lowest in placenta, lung, and kidney. PPP6C can complement mutations in the S. cerevisiae Sit4 and S. pombe ppe1 genes, indicating that PPP6C is the functional homolog of yeast Sit4p and ppe1. Since Sit4p is required for the G1 to S transition of the cell cycle and ppe1 is involved in cell shape control and mitotic division, it has been suggested that PPP6C functions in cell cycle regulation.
Product Categories/Family for anti-PPP6C antibody
References
Yang, J., et al., EMBO J. 24(1):1-10 (2005).
Zhou, G., et al., J. Biol. Chem. 279(45):46595-46605 (2004).
Huang, S., et al., J. Biol. Chem. 279(35):36490-36496 (2004).
Swingle, M.R., et al., J. Biol. Chem. 279(32):33992-33999 (2004).
Wechsler, T., et al., Proc. Natl. Acad. Sci. U.S.A. 101(5):1247-1252 (2004).
Zhou, G., et al., J. Biol. Chem. 279(45):46595-46605 (2004).
Huang, S., et al., J. Biol. Chem. 279(35):36490-36496 (2004).
Swingle, M.R., et al., J. Biol. Chem. 279(32):33992-33999 (2004).
Wechsler, T., et al., Proc. Natl. Acad. Sci. U.S.A. 101(5):1247-1252 (2004).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
35144
NCBI Official Full Name
serine/threonine-protein phosphatase 6 catalytic subunit isoform a
NCBI Official Synonym Full Names
protein phosphatase 6, catalytic subunit
NCBI Official Symbol
PPP6C
NCBI Official Synonym Symbols
PP6; PP6C
NCBI Protein Information
serine/threonine-protein phosphatase 6 catalytic subunit
UniProt Protein Name
Serine/threonine-protein phosphatase 6 catalytic subunit
UniProt Gene Name
PPP6C
UniProt Synonym Gene Names
PPP6; PP6C
UniProt Entry Name
PPP6_HUMAN
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Product Notes
The PPP6C ppp6c (Catalog #AAA286025) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-30. The PPP6C Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PPP6C can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the PPP6C ppp6c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPP6C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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