WB (Western Blot)
Rabbit PRDM16 Polyclonal Antibody | anti-PRDM16 antibody
PRDM16 antibody - middle region
Gene Names
PRDM16; MEL1; KMT8F; LVNC8; PFM13; CMD1LL
Reactivity
Tested Species Reactivity: HumanPredicted Species Reactivity: Human, Rat, Cow, Guinea Pig, Horse, Pig
Applications
Western Blot
Purity
Affinity Purified
Synonyms
PRDM16, Antibody; PRDM16 antibody - middle region; anti-PRDM16 antibody
Host
Rabbit
Reactivity
Tested Species Reactivity: Human
Predicted Species Reactivity: Human, Rat, Cow, Guinea Pig, Horse, Pig
Predicted Species Reactivity: Human, Rat, Cow, Guinea Pig, Horse, Pig
Clonality
Polyclonal
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer and 0.09% (w/v) sodium azide.
Concentration
0.5 mg/ml (varies by lot)
Sequence
Synthetic peptide located within the following region: LNHTQDAKLPSPLGNPALPLVSAVSNSSQGTTAAAGPEEKFESRLEDSCV
Sequence Length
1275
Applicable Applications for anti-PRDM16 antibody
WB (Western Blot)
Homology
Cow: 92%; Dog: 77%; Guinea Pig: 86%; Horse: 85%; Human: 100%; Mouse: 79%; Pig: 92%; Rat: 86%
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of human PRDM16
Protein Size (# AA)
1275 amino acids
Protein Interactions
TFAP4; UBC; HDAC2; Ctbp2; SUMO1; SKI; SMAD3; SMAD2; INADL;
Blocking Peptide
For anti-PRDM16 (MBS3201410) antibody is Catalog #
Preparation and Storage
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
WB (Western Blot)
Related Product Information for anti-PRDM16 antibody
Target Description: The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Product Categories/Family for anti-PRDM16 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
140kDa
NCBI Official Full Name
PR domain zinc finger protein 16 isoform 1
NCBI Official Synonym Full Names
PR/SET domain 16
NCBI Official Symbol
PRDM16
NCBI Official Synonym Symbols
MEL1; KMT8F; LVNC8; PFM13; CMD1LL
NCBI Protein Information
PR domain zinc finger protein 16
UniProt Protein Name
PR domain zinc finger protein 16
UniProt Gene Name
PRDM16
UniProt Synonym Gene Names
KIAA1675; MEL1; PFM13; MDS1/EVI1-like gene 1
UniProt Entry Name
PRD16_HUMAN
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Product Notes
The PRDM16 prdm16 (Catalog #AAA197548) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PRDM16 antibody - middle region reacts with Tested Species Reactivity: Human Predicted Species Reactivity: Human, Rat, Cow, Guinea Pig, Horse, Pig and may cross-react with other species as described in the data sheet. AAA Biotech's PRDM16 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the PRDM16 prdm16 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: LNHTQDAKLP SPLGNPALPL VSAVSNSSQG TTAAAGPEEK FESRLEDSCV. It is sometimes possible for the material contained within the vial of "PRDM16, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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