WB (Western Blot)
(Western blot analysis of extracts of various cell lines using Prdm9 Polyclonal Antibody at 1:1000 dilution.)
Rabbit anti-Mouse, Rat Prdm9 Polyclonal Antibody | anti-Prdm9 antibody
Prdm9 Polyclonal Antibody
Gene Names
Prdm9; Rcr1; Dsbc1; repro7; Meisetz; BC012016; G1-419-29
Reactivity
Mouse, Rat
Applications
Western Blot
Purity
Affinity purification
Synonyms
Prdm9, Antibody; Prdm9 Polyclonal Antibody; Rc; re; Dsbc; Rcr1; Dsbc1; Meise; repro7; Meisetz; PRDM9-B; BC012016; G1-419-29; anti-Prdm9 antibody
Host
Rabbit
Reactivity
Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.05% proclin300,50% glycerol,pH7.3.
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-Prdm9 antibody
WB (Western Blot)
Immunogen
Recombinant fusion protein of mouse Prdm9
Preparation and Storage
Storage: -20 degree C/One year. Avoid freeze/thaw cycles.
WB (Western Blot)
(Western blot analysis of extracts of various cell lines using Prdm9 Polyclonal Antibody at 1:1000 dilution.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines using Prdm9 Polyclonal Antibody at 1:1000 dilution.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines using Prdm9 Polyclonal Antibody at 1:1000 dilution.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines using Prdm9 Polyclonal Antibody at 1:1000 dilution.)
Related Product Information for anti-Prdm9 antibody
Histone methyltransferase that sequentially mono-, di-, and tri-methylates both 'Lys-4' (H3K4 and 'Lys-36' (H3K36 of histone H3 to produce respectively trimethylated 'Lys-4' (H3K4me3 and trimethylated 'Lys-36' (H3K36me3 histone H3 and plays a key role in meiotic prophase by determining hotspot localization thereby promoting meiotic recombination. Also can methylate all four core histones with H3 being the best substrate and the most highly modified. Is also able, on one hand, to mono and di-methylate H4K20 and on other hand to trimethylate H3K9 with the di-methylated H3K9 as the best substrate. During meiotic prophase, binds specific DNA sequences through its zinc finger domains thereby determining hotspot localization where it promotes local H3K4me3 and H3K36me3 enrichment on the same nucleosomes through its histone methyltransferase activity. Thereby promotes double-stranded breaks (DSB formation, at this subset of PRDM9-binding sites, that initiates meiotic recombination for the proper meiotic progression.
Product Categories/Family for anti-Prdm9 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
32,241 Da
NCBI Official Full Name
Histone-lysine N-methyltransferase PRDM9
NCBI Official Synonym Full Names
PR domain containing 9
NCBI Official Symbol
Prdm9
NCBI Official Synonym Symbols
Rcr1; Dsbc1; repro7; Meisetz; BC012016; G1-419-29
NCBI Protein Information
histone-lysine N-methyltransferase PRDM9; VPR domain containing 9; hybrid sterility protein 1; PR-domain zinc finger protein; PR domain-containing protein 9; PR domain zinc finger protein 9; meiosis-induced factor containing a PR/SET domain and zinc-finge
UniProt Protein Name
Histone-lysine N-methyltransferase PRDM9
UniProt Gene Name
Prdm9
UniProt Synonym Gene Names
Hst1; Meisetz
UniProt Entry Name
PRDM9_MOUSE
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Product Notes
The Prdm9 prdm9 (Catalog #AAA179268) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Prdm9 Polyclonal Antibody reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Prdm9 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the Prdm9 prdm9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Prdm9, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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