IHC (Immunohistochemisry)
(Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Prostate Apoptosis Response Protein-4 antibody.)
Rabbit Prostate Apoptosis Response protein-4 Polyclonal Antibody | anti-PAWR antibody
Prostate Apoptosis Response protein-4 Antibody
Gene Names
PAWR; PAR4; Par-4
Reactivity
Human, mouse, rat
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
Prostate Apoptosis Response protein-4, Antibody; Prostate Apoptosis Response protein-4 Antibody; PRKC apoptosis WT1 regulator protein; Prostate apoptosis response 4 protein; Par-4; PAWR; PAR4; anti-PAWR antibody
Host
Rabbit
Reactivity
Human, mouse, rat
Clonality
Polyclonal
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Positions
310-338
Sequence Length
340
Applicable Applications for anti-PAWR antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohistochemisry)
(Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Prostate Apoptosis Response Protein-4 antibody.)
IHC (Immunohistochemisry)
(Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using Prostate Apoptosis Response Protein-4 antibody.)
WB (Western Blot)
(Western blot analysis of extracts from 293 cells The lane on the left is treated with synthesized peptide.)
WB (Western Blot)
(Western blot analysis of extracts from 293 cells The lane on the left is treated with synthesized peptide.)
WB (Western Blot)
(Western blot analysis of lysate from SW620 cell line,using Prostate Apoptosis Response protein-4 Antibody(C0309). C0309 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.)
WB (Western Blot)
(Western blot analysis of lysate from SW620 cell line,using Prostate Apoptosis Response protein-4 Antibody(C0309). C0309 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.)
Related Product Information for anti-PAWR antibody
Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down- regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1.
Product Categories/Family for anti-PAWR antibody
References
Johnstone R.W.,et al.Mol. Cell. Biol. 16:6945-6956(1996).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Hsu S.-C.,et al.Gene 295:109-116(2002).
Chakraborty M.,et al.Cancer Res. 61:7255-7263(2001).
Chang S.,et al.FEBS Lett. 510:57-61(2002).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Hsu S.-C.,et al.Gene 295:109-116(2002).
Chakraborty M.,et al.Cancer Res. 61:7255-7263(2001).
Chang S.,et al.FEBS Lett. 510:57-61(2002).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
36568
NCBI Official Full Name
PRKC apoptosis WT1 regulator protein
NCBI Official Synonym Full Names
PRKC, apoptosis, WT1, regulator
NCBI Official Symbol
PAWR
NCBI Official Synonym Symbols
PAR4; Par-4
NCBI Protein Information
PRKC apoptosis WT1 regulator protein
UniProt Protein Name
PRKC apoptosis WT1 regulator protein
UniProt Gene Name
PAWR
UniProt Synonym Gene Names
PAR4; Par-4
UniProt Entry Name
PAWR_HUMAN
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Product Notes
The PAWR pawr (Catalog #AAA289586) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 310-338. The Prostate Apoptosis Response protein-4 Antibody reacts with Human, mouse, rat and may cross-react with other species as described in the data sheet. AAA Biotech's Prostate Apoptosis Response protein-4 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the PAWR pawr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Prostate Apoptosis Response protein-4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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