IHC (Immunohiostchemistry)
(Anti-Protein C antibody, AAA45084, IHC(P)IHC(P): Human Mammary Cancer Tissue)
Rabbit anti-Human Protein C Polyclonal Antibody | anti-PROC antibody
Anti-Protein C antibody
Gene Names
PROC; PC; APC; PROC1; THPH3; THPH4
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
Protein C, Antibody; Anti-Protein C antibody; Vitamin K-dependent protein C; protein C(inactivator of coagulation factors Va and VIIIa); Activation peptide antibody; Anticoagulant protein C antibody; APC antibody; Autoprothrombin IIA antibody; Blood coagulation factor XIV antibody; EC 3.4.21.69 antibody; PC antibody; proC antibody; PROC_HUMAN antibody; PROC1 antibody; Protein C(inactivator of coagulation factors Va and VIIIa) antibody; THPH3 antibody; THPH4 antibody; Vitamin K dependent protein C antibody; Vitamin K dependent protein C precursor antibody; anti-PROC antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
461
Applicable Applications for anti-PROC antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human Protein C (446-461aa HGHIRDKEAPQKSWAP).
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohiostchemistry)
(Anti-Protein C antibody, AAA45084, IHC(P)IHC(P): Human Mammary Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti-Protein C antibody, AAA45084, IHC(P)IHC(P): Human Mammary Cancer Tissue)
WB (Western Blot)
(Anti-Protein C antibody, AAA45084, Western blottingLane 1: JURKAT Cell LysateLane 2: CEM Cell LysateLane 3: SMMC Cell LysateLane 4: HELA Cell Lysate)
WB (Western Blot)
(Anti-Protein C antibody, AAA45084, Western blottingLane 1: JURKAT Cell LysateLane 2: CEM Cell LysateLane 3: SMMC Cell LysateLane 4: HELA Cell Lysate)
Related Product Information for anti-PROC antibody
Description: Rabbit IgG polyclonal antibody for Vitamin K-dependent protein C(PROC) detection. Tested with WB, IHC-P in Human.
Background: Protein C(PROC), also called PC, is a zymogenic(inactive) protein, the activated form of which plays an important role in regulating blood clotting, inflammation, cell death and maintaining the permeability of blood vessel walls in humans and other animals. The PROC gene is mapped on 2q14.3. The PROC gene contains 8 exons and spans about 11 kb by Foster et al. The conversion of protein C to a protease with anticoagulant function by thrombin requires as a cofactor thrombomodulin, an endothelial cell membrane protein. Riewald et al. demonstrated that activated protein C uses the endothelial cell protein C receptor as a coreceptor for cleavage of protease-activated receptor-1 on endothelial cells. Faust et al. demonstrated that the endothelial pathways required for protein C activation are impaired in severe meningococcal sepsis. They stated that improvement in the outcome of children with meningococcal sepsis who were treated with unactivated protein C concentrates had been described in case reports and in 1 uncontrolled series.
Background: Protein C(PROC), also called PC, is a zymogenic(inactive) protein, the activated form of which plays an important role in regulating blood clotting, inflammation, cell death and maintaining the permeability of blood vessel walls in humans and other animals. The PROC gene is mapped on 2q14.3. The PROC gene contains 8 exons and spans about 11 kb by Foster et al. The conversion of protein C to a protease with anticoagulant function by thrombin requires as a cofactor thrombomodulin, an endothelial cell membrane protein. Riewald et al. demonstrated that activated protein C uses the endothelial cell protein C receptor as a coreceptor for cleavage of protease-activated receptor-1 on endothelial cells. Faust et al. demonstrated that the endothelial pathways required for protein C activation are impaired in severe meningococcal sepsis. They stated that improvement in the outcome of children with meningococcal sepsis who were treated with unactivated protein C concentrates had been described in case reports and in 1 uncontrolled series.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
57,556 Da
NCBI Official Full Name
Vitamin K-dependent protein C
NCBI Official Synonym Full Names
protein C (inactivator of coagulation factors Va and VIIIa)
NCBI Official Symbol
PROC
NCBI Official Synonym Symbols
PC; APC; PROC1; THPH3; THPH4
NCBI Protein Information
vitamin K-dependent protein C; prepro-protein C; autoprothrombin IIA; anticoagulant protein C; blood coagulation factor XIV
UniProt Protein Name
Vitamin K-dependent protein C
UniProt Gene Name
PROC
UniProt Entry Name
PROC_HUMAN
Similar Products
Product Notes
The PROC proc (Catalog #AAA45084) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Protein C antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Protein C can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the PROC proc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Protein C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.