WB (Western Blot)
(Anti-PROC Antibody at 1:1000 dilution + H.plasma whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 52 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Rabbit Protein-C Tag Polyclonal Antibody | anti-PROC antibody
Protein-C Tag Antibody
Gene Names
PROC; PC; APC; PROC1; THPH3; THPH4
Reactivity
Reactivity: HumanPredicted Reactivity: Human
Applications
ELISA, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
Protein-C Tag, Antibody; Protein-C Tag Antibody; Vitamin K-dependent protein C; Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV; Vitamin K-dependent protein C light chain; Vitamin K-dependent protein C heavy chain; Activation peptide; PROC; anti-PROC antibody
Host
Rabbit
Reactivity
Reactivity: Human
Predicted Reactivity: Human
Predicted Reactivity: Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
KLH conjugated synthetic peptide encoding the Protein-C epitope tag (CEDQVDPRLIDGK) was used as antigen.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Applicable Applications for anti-PROC antibody
ELISA, WB (Western Blot)
Function
Protein C is a vitamin K-dependent serine protease that regulates blood coagulation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids (PubMed:25618265). Exerts a protective effect on the endothelial cell barrier function (PubMed:25651845).
Cellular Location
Secreted. Golgi apparatus Endoplasmic reticulum
Tissue Location
Plasma; synthesized in the liver.
Preparation and Storage
Maintain refrigerated at 2-8 degrees C for up to 2 weeks. For long term storage store at -20 degrees C in small aliquots to prevent freeze-thaw cycles.
WB (Western Blot)
(Anti-PROC Antibody at 1:1000 dilution + H.plasma whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 52 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
WB (Western Blot)
(Anti-PROC Antibody at 1:1000 dilution + H.plasma whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 52 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
WB (Western Blot)
(Western blot analysis of anti-Protein-C tag Pab in Protein-C-tagged recombinant protein bacterial lysate.)
WB (Western Blot)
(Western blot analysis of anti-Protein-C tag Pab in Protein-C-tagged recombinant protein bacterial lysate.)
Related Product Information for anti-PROC antibody
Epitope tags consisting of short sequences recognized by well-characterizated antibodies have been widely used in the study of protein expression in various systems. The epitope tag composed of a 12 residue peptide, EDQVDPRLIDGK, is derived from Protein-C, a vitamin K-dependent serine protease that regulates blood coagluation by inactivating factors Va and VIIIa in the presence of calcium ions and phospholipids.
AAA Biotech's anti-Protein-C polyclonal antibody provides a simple solution to detect the expression of a Protein-C epitope-tagged protein in cells.
AAA Biotech's anti-Protein-C polyclonal antibody provides a simple solution to detect the expression of a Protein-C epitope-tagged protein in cells.
Product Categories/Family for anti-PROC antibody
References
Lichty JJ, Malecki JL, Agnew HD, Michelson-Horowitz DJ, Tan S. Comparison of affinity tags for protein purification. Protein Expr Purif. 2005 May;41(1):98-105.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
vitamin K-dependent protein C preproprotein
NCBI Official Synonym Full Names
protein C (inactivator of coagulation factors Va and VIIIa)
NCBI Official Symbol
PROC
NCBI Official Synonym Symbols
PC; APC; PROC1; THPH3; THPH4
NCBI Protein Information
vitamin K-dependent protein C
UniProt Protein Name
Vitamin K-dependent protein C
UniProt Gene Name
PROC
UniProt Entry Name
PROC_HUMAN
Similar Products
Product Notes
The PROC proc (Catalog #AAA289892) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Protein-C Tag Antibody reacts with Reactivity: Human Predicted Reactivity: Human and may cross-react with other species as described in the data sheet. AAA Biotech's Protein-C Tag can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the PROC proc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Protein-C Tag, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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