Rabbit anti-Human PSMD2 Polyclonal Antibody | anti-PSMD2 antibody

Rabbit anti-PSMD2 Antibody, Affinity Purified

Cat. Num. AAA212320

• Gene Names: PSMD2; S2; P97; Rpn1; TRAP2
• Reactivity: Human
• Applications: Immunoprecipitation, Western Blot
• Purity: Antigen Affinity Purified
• Synonyms: PSMD2, Antibody; Rabbit anti-PSMD2 Antibody, Affinity Purified; proteasome (prosome, macropain) 26S subunit, non-ATPase, 2; tumor necrosis factor type 1 receptor-associated protein 2; TRAP2; TNFR-associated protein 2; S2; protein 55.11; P97; 55.11 protein; 26S proteasome subunit p97; 26S proteasome regulatory subunit S2; 26S proteasome regulatory subunit RPN1; 26S proteasome non-ATPase regulatory subunit 2; RPN1; proteasome 26S subunit, non-ATPase 2; anti-PSMD2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Purity/Purification: Antigen Affinity Purified
• Form/Format: Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
• Concentration: 1000ug/ml (varies by lot)

• Applicable Applications for anti-PSMD2 antibody: IP (Immunoprecipitation), WB (Western Blot)
• Predicted Reactivity: Orangutan
• Immunogen: Between 1 and 50
• Conjugation: Unconjugated
• Preparation and Storage: Store at 2-8 degree C; Shelf Life: 1 year from date of receipt

WB (Western Blot)

(Detection of human PSMD2 by western blot. Samples: Whole cell lysate from HEK293T (15 and 50 ug), HeLa (H; 50 ug) and Jurkat (J; 50 ug) cells. Antibodies: Affinity purified rabbit anti-PSMD2 antibody AAA212320 (lot AAA212320-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.)

IP (Immunoprecipitation)

(Detection of human PSMD2 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from HEK293T cells. Antibodies: Affinity purified rabbit anti-PSMD2 antibody AAA212320 (lot AAA212320-1) used for IP at 6 ug/mg lysate. PSMD2 was also immunoprecipitated by rabbit anti-PSMD2 antibody For blotting immunoprecipitated PSMD2, AAA212320 was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 seconds.)

Related Product Information for anti-PSMD2 antibody

PSMD2 [proteasome (prosome, macropain) 26S subunit, non-ATPase, 2] is a subunit of the 26 S proteasome. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD2 is a subunit of the 19S regulator lid, which is responsible for substrate recognition and binding [taken from NCBI Entrez Gene (Gene ID: 5708)].

Product Categories/Family for anti-PSMD2 antibody

Primary Antibodies

NCBI and Uniprot Product Information

• NCBI GI #: 25777602
• NCBI GeneID: 5708
• NCBI Accession #: NP_002799.3
• NCBI GenBank Nucleotide #: NM_002808.3
• UniProt Accession #: Q13200; Q12932; Q15321; Q53XQ4; Q96I12
• Molecular Weight: 100,200 Da
• NCBI Official Full Name: 26S proteasome non-ATPase regulatory subunit 2
• NCBI Official Synonym Full Names: proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
• NCBI Official Symbol: PSMD2
• NCBI Official Synonym Symbols: S2; P97; Rpn1; TRAP2
• NCBI Protein Information: 26S proteasome non-ATPase regulatory subunit 2; 55.11 protein; protein 55.11; TNFR-associated protein 2; 26S proteasome subunit p97; 26S proteasome regulatory subunit S2; 26S proteasome regulatory subunit RPN1; tumor necrosis factor receptor-associated pr
• UniProt Protein Name: 26S proteasome non-ATPase regulatory subunit 2
• UniProt Gene Name: PSMD2
• UniProt Synonym Gene Names: TRAP2
• UniProt Entry Name: PSMD2_HUMAN