FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of MCF-7 cells with Pygopus 2 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated Goat anti rabbit IgG was used as the secondary antibody.)
Rabbit anti-Human, Mouse Pygopus 2 Polyclonal Antibody | anti-PYGO2 antibody
Pygopus 2 Antibody
Gene Names
PYGO2; 1190004M21Rik
Reactivity
Human, Mouse
Applications
Flow Cytometry, Functional Assay, Western Blot
Purity
Peptide affinity purified
Synonyms
Pygopus 2, Antibody; Pygopus 2 Antibody; 1190004M21Rik antibody; FLJ33226 antibody; PP7910 antibody; PYGO2 antibody; Pygo2 protein antibody; PYGO2_HUMAN antibody; Pygopus 2 antibody; pygopus homolog 2 (Drosophila) antibody; Pygopus homolog 2 antibody; anti-PYGO2 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Peptide affinity purified
Form/Format
1*TBS (pH7.4), 1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Applicable Applications for anti-PYGO2 antibody
FCM/FACS (Flow Cytometry), WB (Western Blot)
Immunogen
Peptide
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C.
FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of MCF-7 cells with Pygopus 2 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated Goat anti rabbit IgG was used as the secondary antibody.)
FCM/FACS (Flow Cytometry)
(Flow cytometric analysis of MCF-7 cells with Pygopus 2 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated Goat anti rabbit IgG was used as the secondary antibody.)
WB (Western Blot)
(Western blot analysis on NCCIT (1) and Hela (2) cell lysates using anti-Pygopus 2 rabbit polyclonal antibody.)
WB (Western Blot)
(Western blot analysis on NCCIT (1) and Hela (2) cell lysates using anti-Pygopus 2 rabbit polyclonal antibody.)
Related Product Information for anti-PYGO2 antibody
Pygopus 2, also known as PYGO2, is a 406 amino acid protein that is the human homolog of the Drosophila pygopus protein. Localized to the nucleus, Pygopus 2 contains one PHD finger that interacts with the homology domain of the Wnt signaling protein Bcl-9. This interaction joins Pygopus 2 with the -catenin/TCF complex (a crucial complex in Wnt signaling), thereby allowing -catenin to transcriptionally activate Wnt target genes. Association of Pygopus 2 with proteins involved in the Wnt signaling pathway is thought to regulate proper signal transduction, as absence of the Pygopus 2/-catenin interaction may play a role in development of B-cell malignancies. In addition, Pygopus 2 expression is upregulated in and required for the growth of breast cancer cells, suggesting a crucial role in carcinogenesis.
Product Categories/Family for anti-PYGO2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
41,244 Da
NCBI Official Full Name
Homo sapiens pygopus family PHD finger 2 (PYGO2), mRNA
NCBI Official Synonym Full Names
pygopus family PHD finger 2
NCBI Official Symbol
PYGO2
NCBI Official Synonym Symbols
1190004M21Rik
NCBI Protein Information
pygopus homolog 2; pygopus 2
UniProt Protein Name
Pygopus homolog 2
UniProt Gene Name
PYGO2
UniProt Entry Name
PYGO2_HUMAN
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Product Notes
The PYGO2 pygo2 (Catalog #AAA311964) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Pygopus 2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Pygopus 2 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), WB (Western Blot). Researchers should empirically determine the suitability of the PYGO2 pygo2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Pygopus 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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