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product-image-AAA229514_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of paraffin-embedded human colon cancer using AAA229514 at dilution 1:100)

Rabbit anti-Human Pyrroline-5-carboxylate reductase 1, mitochondrial Polyclonal Antibody | anti-PYCR1 antibody

Rabbit anti-human Pyrroline-5-carboxylate reductase 1, mitochondrial polyclonal Antibody

Gene Names
PYCR1; P5C; P5CR; PRO3; PYCR; PIG45; PP222; ARCL2B; ARCL3B
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Purity
Caprylic Acid Ammonium Sulfate Precipitation purified
Synonyms
Pyrroline-5-carboxylate reductase 1, mitochondrial, Antibody; Rabbit anti-human Pyrroline-5-carboxylate reductase 1, mitochondrial polyclonal Antibody; P5C reductase 1; P5CR 1; PYCR1; anti-PYCR1 antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation purified
Form/Format
Liquid
Sequence Length
319
Applicable Applications for anti-PYCR1 antibody
IHC (Immunohistochemistry), ELISA
Immunogen
Recombinant human Pyrroline-5-carboxylate reductase 1, mitochondrial protein
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Preparation and Storage
Shipped at 4 degree C. Upon delivery, aliquot and store at -20 degree C or -80 degree C.

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded human colon cancer using AAA229514 at dilution 1:100)

product-image-AAA229514_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of paraffin-embedded human colon cancer using AAA229514 at dilution 1:100)

IHC (Immunohistochemistry)

(Immunohistochemistry of paraffin-embedded human breast cancer using AAA229514 at dilution 1:100)

product-image-AAA229514_IHC15.jpg IHC (Immunohistochemistry) (Immunohistochemistry of paraffin-embedded human breast cancer using AAA229514 at dilution 1:100)
Related Product Information for anti-PYCR1 antibody
Housekeeping enzyme that catalyzes the last step in proline biosynthesis. Can utilize both NAD and NADP, but has higher affinity for NAD. Involved in the cellular response to oxidative stress.

This gene encodes an enzyme that catalyzes the NAD(P)H-dependent conversion of pyrroline-5-carboxylate to proline. This enzyme may also play a physiologic role in the generation of NADP(+) in some cell types. The protein forms a homopolymer and localizes to the mitochondrion. Alternate splicing results in two transcript variants encoding different isoforms.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
35,981 Da
NCBI Official Full Name
pyrroline-5-carboxylate reductase 1, mitochondrial isoform 1
NCBI Official Synonym Full Names
pyrroline-5-carboxylate reductase 1
NCBI Official Symbol
PYCR1
NCBI Official Synonym Symbols
P5C; P5CR; PRO3; PYCR; PIG45; PP222; ARCL2B; ARCL3B
NCBI Protein Information
pyrroline-5-carboxylate reductase 1, mitochondrial
UniProt Protein Name
Pyrroline-5-carboxylate reductase 1, mitochondrial
UniProt Gene Name
PYCR1
UniProt Synonym Gene Names
P5C reductase 1; P5CR 1
UniProt Entry Name
P5CR1_HUMAN

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Product Notes

The PYCR1 pycr1 (Catalog #AAA229514) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Pyrroline-5-carboxylate reductase 1, mitochondrial polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Pyrroline-5-carboxylate reductase 1, mitochondrial can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the PYCR1 pycr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Pyrroline-5-carboxylate reductase 1, mitochondrial, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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