IF (Immunofluorescence)
(Immunofluorescence of RABEX5 in mouse brain tissue with RABEX5 antibody at 20 μg/mL.)
Rabbit RABEX5 Polyclonal Antibody | anti-RABGEF1 antibody
RABEX5 Antibody
Gene Names
RABGEF1; RAP1; RABEX5; rabex-5
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
RABEX5 Antibody is affinity chromatography purified via peptide column.
Synonyms
RABEX5, Antibody; RABEX5 Antibody; RABEX5; RAP1; rabex-5; RAB guanine nucleotide exchange factor (GEF) 1; anti-RABGEF1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
At least four isoforms of RABEX5 are known to exist; this antibody will recognize all four. RABEX5 antibody is predicted to not cross-react with other LRRFIP family members.
Purity/Purification
RABEX5 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
491
Applicable Applications for anti-RABGEF1 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
RABEX5 antibody was raised against a 19 amino acid synthetic peptide near the center terminus of human RABEX5.
Buffer
RABEX5 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
RABEX5 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of RABEX5 in mouse brain tissue with RABEX5 antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of RABEX5 in mouse brain tissue with RABEX5 antibody at 20 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of RABEX5 in mouse brain tissue with RABEX5 antibody at 5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of RABEX5 in mouse brain tissue with RABEX5 antibody at 5 μg/mL.)
WB (Western Blot)
(Western blot analysis of RABEX5 in human liver tissue lysate with RABEX5 antibody at (A) 1 and (B) 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of RABEX5 in human liver tissue lysate with RABEX5 antibody at (A) 1 and (B) 2 μg/mL.)
Related Product Information for anti-RABGEF1 antibody
RABEX5 Antibody: RABEX5 is a guanine nucleotide exchange factor (GEF) that forms a complex with rabaptin-5 and specifically activates Rab5, a small GTPase that plays an essential role in endocytic traffic. RABEX-5 is thought to also interact with another member of the Rab family, Rab22, which targets RABEX5 to early endosomes, allowing it to activate Rab5 and thereby promote Rab5-mediated endosome fusion.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
58,526 Da
NCBI Official Full Name
rab5 GDP/GTP exchange factor isoform c
NCBI Official Synonym Full Names
RAB guanine nucleotide exchange factor (GEF) 1
NCBI Official Symbol
RABGEF1
NCBI Official Synonym Symbols
RAP1; RABEX5; rabex-5
NCBI Protein Information
rab5 GDP/GTP exchange factor; rabaptin-5-associated exchange factor for Rab5
UniProt Protein Name
Rab5 GDP/GTP exchange factor
UniProt Gene Name
RABGEF1
UniProt Synonym Gene Names
RABEX5
UniProt Entry Name
RABX5_HUMAN
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Product Notes
The RABGEF1 rabgef1 (Catalog #AAA40105) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RABEX5 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's RABEX5 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the RABGEF1 rabgef1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RABEX5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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