Rabbit anti-Human RAIDD Polyclonal Antibody | anti-CRADD antibody

RAIDD Antibody

Cat. Num. AAA39624

• Gene Names: CRADD; MRT34; RAIDD
• Reactivity: Human
• Applications: Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
• Purity: RAIDD Antibody is affinity chromatography purified via peptide column.
• Synonyms: RAIDD, Antibody; RAIDD Antibody; RAIDD; MRT34; Death domain-containing protein CRADD; Caspase and RIP adapter with death domain; CASP2 and RIPK1 domain containing adaptor with death domain; anti-CRADD antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: RAIDD Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Sequence Length: 199

• Applicable Applications for anti-CRADD antibody: IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: RAIDD antibody was raised against a 19 amino acid peptide near the center of human RAIDD.
• Buffer: RAIDD Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: RAIDD antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of RAIDD in Hela cells with RAIDD antibody at 20 μg/mL.)

IF (Immunofluorescence)

(Immunofluorescence of RAIDD in Hela cells with RAIDD antibody at 20 μg/mL.)

ICC (Immunocytochemistry)

(Immunocytochemistry of RAIDD in HeLa cells with RAIDD antibody at 5 μg/mL.)

WB (Western Blot)

(Western blot analysis of RAIDD in whole cell lysates from HeLa (H) or K562 (K) cells with RAIDD antibody at 1:500 dilution.)

Related Product Information for anti-CRADD antibody

RAIDD Antibody: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain (DD)-containing receptors, TNFR1 and Fas. The death signals are transduced by a group of DD-containing adapter molecules. A novel cell death adapter was recently identified by two independent groups and designated RAIDD (RIP-associated ICH-1/CED-3-homologous protein with DD) and CRADD (caspase and RIP adapter with DD)1, RAIDD contains a DD and a CARD (for caspase recruitment domain) which interact with RIP and caspase, respectively, to transduce death signals1, 3. RAIDD is constitutively expressed in many tissues and mediates apoptosis caused by Fas and TNFR-1.

NCBI and Uniprot Product Information

• NCBI GI #: 1785557
• NCBI GeneID: 8738
• UniProt Accession #: P78560; B7Z2Q5
• Molecular Weight: 22 kDa
• NCBI Official Full Name: death adaptor molecule RAIDD
• NCBI Official Synonym Full Names: CASP2 and RIPK1 domain containing adaptor with death domain
• NCBI Official Symbol: CRADD
• NCBI Official Synonym Symbols: MRT34; RAIDD
• NCBI Protein Information: death domain-containing protein CRADD; death adaptor molecule RAIDD; caspase and RIP adaptor with death domain; RIP-associated protein with a death domain; RIP-associated ICH1/CED3-homologous protein with death domain
• UniProt Protein Name: Death domain-containing protein CRADD
• UniProt Gene Name: CRADD
• UniProt Synonym Gene Names: RAIDD
• UniProt Entry Name: CRADD_HUMAN