IHC (Immunohiostchemistry)
(RHOC Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RHOC Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit RHOC Polyclonal Antibody | anti-RHOC antibody
RHOC Antibody (C-term)
Gene Names
RHOC; H9; ARH9; ARHC; RHOH9
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
RHOC, Antibody; RHOC Antibody (C-term); Rho-related GTP-binding protein RhoC; Rho cDNA clone 9; h9; RHOC; ARH9; ARHC; anti-RHOC antibody
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine, Mouse)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This RHOC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from the C-terminal region of human RHOC.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
102-130
Sequence Length
193
Applicable Applications for anti-RHOC antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(RHOC Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RHOC Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(RHOC Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RHOC Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(RHOC Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the RHOC antibody detected the RHOC protein (arrow).)
WB (Western Blot)
(RHOC Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the RHOC antibody detected the RHOC protein (arrow).)
Related Product Information for anti-RHOC antibody
This gene encodes a member of the Rho family of small
GTPases, which cycle between inactive GDP-bound and active
GTP-bound states and function as molecular switches in signal
transduction cascades. Rho proteins promote reorganization of the
actin cytoskeleton and regulate cell shape, attachment, and
motility. The protein encoded by this gene is prenylated at its
C-terminus, and localizes to the cytoplasm and plasma membrane. It
is thought to be important in cell locomotion. Overexpression of
this gene is associated with tumor cell proliferation and
metastasis. Multiple alternatively spliced variants, encoding the
same protein, have been identified.
GTPases, which cycle between inactive GDP-bound and active
GTP-bound states and function as molecular switches in signal
transduction cascades. Rho proteins promote reorganization of the
actin cytoskeleton and regulate cell shape, attachment, and
motility. The protein encoded by this gene is prenylated at its
C-terminus, and localizes to the cytoplasm and plasma membrane. It
is thought to be important in cell locomotion. Overexpression of
this gene is associated with tumor cell proliferation and
metastasis. Multiple alternatively spliced variants, encoding the
same protein, have been identified.
Product Categories/Family for anti-RHOC antibody
References
Jiang, L., et al. Int. J. Cancer 127(3):505-512(2010)
Wu, M., et al. Cancer 116 (11 SUPPL), 2768-2782 (2010) :
Lipkin, S.M., et al. Cancer Prev Res (Phila) 3(5):597-603(2010)
Kitzing, T.M., et al. Oncogene 29(16):2441-2448(2010)
Segat, L., et al. Vaccine 28(10):2201-2206(2010)
Wu, M., et al. Cancer 116 (11 SUPPL), 2768-2782 (2010) :
Lipkin, S.M., et al. Cancer Prev Res (Phila) 3(5):597-603(2010)
Kitzing, T.M., et al. Oncogene 29(16):2441-2448(2010)
Segat, L., et al. Vaccine 28(10):2201-2206(2010)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
22006
NCBI Official Full Name
rho-related GTP-binding protein RhoC
NCBI Official Synonym Full Names
ras homolog family member C
NCBI Official Symbol
RHOC
NCBI Official Synonym Symbols
H9; ARH9; ARHC; RHOH9
NCBI Protein Information
rho-related GTP-binding protein RhoC
UniProt Protein Name
Rho-related GTP-binding protein RhoC
UniProt Gene Name
RHOC
UniProt Synonym Gene Names
ARH9; ARHC; h9
UniProt Entry Name
RHOC_HUMAN
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Product Notes
The RHOC rhoc (Catalog #AAA286839) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 102-130. The RHOC Antibody (C-term) reacts with Human (Predicted Reactivity: Bovine, Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's RHOC can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the RHOC rhoc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RHOC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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