Rabbit anti-Human RISC-loading complex subunit TARBP2 Polyclonal Antibody | anti-TARBP2 antibody
Rabbit anti-human RISC-loading complex subunit TARBP2 polyclonal Antibody(TARBP2)
Gene Names
TARBP2; LOQS; TRBP; TRBP1; TRBP2
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purified
Synonyms
RISC-loading complex subunit TARBP2, Antibody; Rabbit anti-human RISC-loading complex subunit TARBP2 polyclonal Antibody(TARBP2); TAR RNA-binding protein 2; Trans-activation-responsive RNA-binding protein; TARBP2; TRBP; anti-TARBP2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
345
Applicable Applications for anti-TARBP2 antibody
IHC (Immunohistochemistry), ELISA
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human RISC-loading complex subunit TARBP2 protein (1-366aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-27612 / sc-292550 / sc-134110
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Related Product Information for anti-TARBP2 antibody
Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from double-stranded RNA (dsRNA) by DICER1. Binds to the HIV-1 TAR RNA which is located in the long terminal repeat (LTR) of HIV-1, and stimulates translation of TAR-containing RNAs. This is achieved in part at least by binding to and inhibiting EIF2AK2/PKR, thereby reducing phosphorylation and inhibition of EIF2S1/eIF-2-alpha. May also promote translation of TAR-containing RNAs independently of EIF2AK2/PKR.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
36,916 Da
NCBI Official Full Name
RISC-loading complex subunit TARBP2 isoform b
NCBI Official Synonym Full Names
TAR (HIV-1) RNA binding protein 2
NCBI Official Symbol
TARBP2
NCBI Official Synonym Symbols
LOQS; TRBP; TRBP1; TRBP2
NCBI Protein Information
RISC-loading complex subunit TARBP2
UniProt Protein Name
RISC-loading complex subunit TARBP2
UniProt Gene Name
TARBP2
UniProt Entry Name
TRBP2_HUMAN
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Product Notes
The TARBP2 tarbp2 (Catalog #AAA119641) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human RISC-loading complex subunit TARBP2 polyclonal Antibody(TARBP2) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RISC-loading complex subunit TARBP2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the TARBP2 tarbp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RISC-loading complex subunit TARBP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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