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product-image-AAA231524_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of paraffin-embedded human kidney tissue using AAA231524 at dilution of 1:100)

Rabbit anti-Human RNF139 Polyclonal Antibody | anti-RNF139 antibody

RNF139 Antibody

Gene Names
RNF139; RCA1; TRC8; HRCA1
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purified
Synonyms
RNF139, Antibody; RNF139 Antibody; E3 ubiquitin-protein ligase RNF139; RING finger protein 139; Translocation in renal carcinoma on chromosome 8 protein; RNF139; anti-RNF139 antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
664
Applicable Applications for anti-RNF139 antibody
IHC (Immunohistochemistry), ELISA
Species
Human
Immunogen
Recombinant human E3 ubiquitin-protein ligase RNF139 protein (C-155AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-67885 / sc-68373
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded human kidney tissue using AAA231524 at dilution of 1:100)

product-image-AAA231524_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of paraffin-embedded human kidney tissue using AAA231524 at dilution of 1:100)

IHC (Immunohistochemistry)

(Immunohistochemistry of paraffin-embedded human placenta tissue using AAA231524 at dilution of 1:100)

product-image-AAA231524_IHC15.jpg IHC (Immunohistochemistry) (Immunohistochemistry of paraffin-embedded human placenta tissue using AAA231524 at dilution of 1:100)
Related Product Information for anti-RNF139 antibody
E3-ubiquitin ligase; acts as a negative regulator of the cell proliferation through mechanisms involving G2/M arrest and cell death. Required for MHC class I ubiquitination in cells expressing the cytomegalovirus protein US2 before dislocation from the endoplasmic reticulum (ER). Affects SREBP processing by hindering the SREBP/SCAP complex translocation from the ER to the Golgi, thereby reducing SREBF2 target gene expression. Required for INSIG1 ubiquitination. May be required for EIF3 complex ubiquitination. May function as a signaling receptor.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
75,994 Da
NCBI Official Full Name
E3 ubiquitin-protein ligase RNF139
NCBI Official Synonym Full Names
ring finger protein 139
NCBI Official Symbol
RNF139
NCBI Official Synonym Symbols
RCA1; TRC8; HRCA1
NCBI Protein Information
E3 ubiquitin-protein ligase RNF139
UniProt Protein Name
E3 ubiquitin-protein ligase RNF139
UniProt Gene Name
RNF139
UniProt Entry Name
RN139_HUMAN

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Product Notes

The RNF139 rnf139 (Catalog #AAA231524) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RNF139 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RNF139 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the RNF139 rnf139 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RNF139, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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